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Last updated December 3, 2009. Please note that this site represents the latest program changes
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Plenary Session

Oral and Poster Abstracts
Oral Session
Sunday, December 6, 2009: 2:00 PM-4:00 PM
Hall F (Ernest N. Morial Convention Center)
2:00 PM
Dabigatran Etexilate Versus Warfarin in the Treatment of Venous ThromboembolismClinically Relevant Abstract

Sam Schulman1*, Henry Eriksson2*, Samuel Z. Goldhaber3, Ajay K Kakkar, MD, PhD4, Clive Kearon5, Patrick Mismetti6*, Sebastian M Schellong7*, David Baanstra8* and Janet Schnee9*

1Department of Medicine, McMaster University, Hamilton, ON, Canada
2Sahlgrenska University Hospital-Östra, Gothenburg, Sweden
3Brigham & Women's Hospital, Boston, MA
4Barts and the London School of Medicine, Thrombosis Research Institute, London, United Kingdom
5Henderson Hospital, McMaster University Clinic, Hamilton, ON, Canada
6Vascular pathology, Bellevue Hospital, Saint Etienne, France
7Medical Division 2, Municipal Hospital Friedrichstadt, Dresden, Germany
8Clinical Research, Boehringer Ingelheim, Alkmaar, Netherlands
9Boehringer Ingelheim, Ridgefield, CT

2:15 PM
Coordinated Regulation of Hematopoietic and Mesenchymal Stem Cells in a Bone Marrow Niche

Simón Méndez-Ferrer, PhD1, Tatyana V. Michurina2*, Francesca Ferraro3*, Amin Mazloom1*, Ben MacArthur1*, Sergio Lira, MD, PhD1*, David T. Scadden, MD3, Avi Ma'ayan1*, Grigori N. Enikolopov, PhD2* and Paul S. Frenette, MD1

1Mount Sinai School of Medicine, New York, NY
2Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
3MGH Center for Regenerative Medicine, Boston, MA

2:30 PM
A Prospective, Multicenter, Randomized, Trial of Bortezomib/Melphalan/Prednisone (VMP) Versus Bortezomib/Thalidomide/Prednisone (VTP) as Induction Therapy Followed by Maintenance Treatment with Bortezomib/Thalidomide (VT) Versus Bortezomib/Prednisone (VP) in Elderly Untreated Patients with Multiple Myeloma Older Than 65 Years

Maria-Victoria Mateos, MD, PhD1*, Albert Oriol, MD2*, Joaquin Martinez, MD3*, Mª Teresa Cibeira4*, Norma C. Gutiérrez5*, Maria Jose Terol, MD6*, Raquel de Paz, MD, PhD7*, Jose García-Laraña8*, Enrique Bengoechea9*, Alejandro Martín García-Sancho10*, Rafael Martínez11*, Luis Palomera12*, Felipe de Arriba13*, Yolanda Gonzalez14*, José Hernández15*, Anna Sureda, MD, PhD16*, Jose-Luis Bello17*, Juan José Lahuerta, MD, PhD18*, Joan Blade, M.D.19 and Jesús F. San-Miguel, MD, PhD20

1Haematology, Hospital Universitario de Salamanca, Salamanca, Spain
2Hospital Universitari Germans Trias i Pujol, Badalona, Spain
3Hematology, Hospital Doce de Octubre, Madrid
4Hematology, Hospital Clinic i Provincial, Barcelona, Spain
5Hematology, Hospital Universitario de Salamanca; Centro de Investigación del Cáncer (CIC, IBMCC USAL-CSIC), Salamanca, Spain
6Hospital Clinico Universitario de Valencia, Barcelona, Spain
7Hematology, Hospital Universitario La Paz, Madrid, Spain
8Hemaology, Hospital Ramón y Cajal, Madrid, Spain
9PETHEMA/Spanish Myeloma Group
10Hospital Virgen de la Concha, Zamora, Spain
11Hematology, Hospital Clínico San Carlos, Madrid, Spain
12Hospital Lozano Blesa, Zaragoza, Spain
13Hematology, Hospital Morales Meseguer, Murcia, Spain
14Hospital Josep Trueta, Girona, Spain
15Hospital General de Segovia, Segovia, Spain
16Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
17Hospital Clinico Universitario de Santiago de Compostela, Santiago de Compostela, Spain
18Hospital 12 de Octubre, Madrid, Spain
19Hospital Clinic, IDIBAPS, Barcelona, Spain
20Po. San Vicente, 58-182, Hospital Clinico Universitario de Salamanca, Salamanca, Spain

2:45 PM
Adoptive Immunotherapy  with Tregs Prevents GvHD and Favours Immune Reconstitution After HLA Haploidentical Transplants for Hematological Malignancies

Mauro Di Ianni1*, Franca Falzetti1, Alessandra Carotti1*, Adelmo Terenzi1*, Elisabetta Bonifacio1*, Yair Reisner2, Andrea Velardi1, Franco Aversa1* and Massimo F Martelli1*

1Department of Clinical and Experimental Medicine, Hematology and Clinical Immunology Section, Perugia, Italy
2Department of Immunology, Weizmann Institute of Science, Rehovot, Israel

3:00 PM
Control of Hemoglobin Switching by BCL11A

Jian Xu, PhD1*, Vijay G. Sankaran, MD, PhD1*, Yuko Fujiwara, PhD1* and Stuart H. Orkin, MD2

1Division of Hematology/Oncology, Children's Hospital Boston, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA
2Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

3:15 PM
Improving the Treatment Outcome of Acute Promyelocytic Leukemia in Developing Countries through International Cooperative Network. Report On the International Consortium On Acute Promyelocytic Leukemia Study GroupClinically Relevant Abstract

Eduardo M Rego1, Haesook T. Kim2*, Guillermo J. Ruiz-Arguelles3, Rosario Uriarte4*, Rafael H Jacomo5, Homero Gutiérrez-Aguirre6*, Raul AM Melo7*, Rosane Bittencourt8*, Ricardo Pasquini9, Katia BB Pagnano10, Evandro M Fagundes11, Maria de Lourdes LF Chauffaille12*, Carlos Chiattone13, Lem Martinez4*, Luis A Meillon14, David Gomez-Almaguer6, Hau C. Kwaan15, Javier Garces-Eisele3*, Robert E Gallagher16, Charlotte M Niemeyer17, Bob Lowenberg18, Raul C Ribeiro19, Francesco Lo-Coco20* and Miguel A Sanz21*

1Hematology Service, Internal Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil
2Dana Farber Cancer Institute, Boston, MA
3Clinica Ruiz de Puebla, Puebla, Mexico
4Asociacion Espanola Primera de Socorros Mutuos, Montevideo, Uruguay
5Internal Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil
6Hematology, Hospital Universitario, Monterrey, Mexico
7HEMOPE, Recife, Brazil
8Hematology and BMT, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
9Federal Univeristy of Parana, Curitiba, Brazil
10Internal Medicine-Hematology, UNICAMP, Campinas, Brazil
11Hematology, Federal University of Minas Gerais, Belo Horizonte, Brazil
12Hematology and Transfusion Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil
13Hematology/Oncology, Santa Casa Medical School, Sao Paulo, Brazil
14Centro Médico Nacional Siglo XXI, Mexico, Mexico
15Northwestern University, Chicago, IL
16Medicine and Oncology, Albert Einstein Cancer Center, Bronx, NY
17Dept. of Pediatrics and Adolescent Medicine, University Medical Center, Freiburg, Germany
18Hematology, Erasmus University Medical Center, Rotterdam, Netherlands
19St. Jude Children's Rsch. Hosp., Memphis, TN
20University of Tor Vergata, Rome, Italy
21Hospital Universitario La Fe, Valencia, Spain

*signifies non-member of ASH