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Last updated December 3, 2009. Please note that this site represents the latest program changes
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401.O1.6 Basic Science and Clinical Practice in Blood Transfusion: Transfusion Medicine - Clinical Research

Oral and Poster Abstracts
Oral Session
Sunday, December 6, 2009: 4:30 PM-6:00 PM
288-290 (Ernest N. Morial Convention Center)
Moderators:
Ravindra Sarode, MD and Darrell Triulzi, MD
4:30 PM
Mechanism of Transfusion-Related Acute Lung Injury Induced by HLA Class II Antibodies

Ulrich J Sachs, MD, PhD1*, Wiebke Wasel1*, Angelika Reil, MD2*, Juergen Bux, MD, PhD2, Gregor Bein, MD, PhD1*, Sentot Santoso, PhD1 and Norbert Weissmann, PhD3*

1Institute for Clinical Immunology and Transfusion Medicine, Justus Liebig University Giessen, Giessen, Germany
2DRK-Blutspendedienst West, Hagen, Germany
3University of Giessen Lung Center, Justus Liebig University Giessen, Giessen, Germany

4:45 PM
Experience with a Therapeutic Platelet Transfusion Strategy in Acute Myeloid Leukemia: Preliminary Results of a Randomized Multicenter Study After Enrolment of 175 Patients

Hannes Wandt, MD1*, Kerstin Schaefer-Eckart, MD1, Bettina Pilz1*, Markus Thalheimer, MD2*, Anthony D Ho, MD, PhD2*, Markus Schaich, MD3, Martin Kaufmann, MD4*, Walter E. Aulitzky, MD4, Mathias Haenel, MD5*, Regina Herbst, MD5*, Gottfried Doelken, MD6, Anne Friederike Klenner, MD6*, Mathias Freund, MD7, Christian Junghanss, MD7* and Gerhard Ehninger, MD8

1Medical Department 5, Klinikum Nord, Nuremberg, Germany
2Internal Medicine V - Haematology/Oncology, University of Heidelberg, Germany
3Medical Clinic 1, University Hospital, Dresden, Germany
4Robert-Bosch-Krankenhaus, Stuttgart, Germany
5Clinic of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany
6Clinic of Internal Medicine C, University of Greifswald, Germany
7Hematology/Oncology, University of Rostock, Germany
8Medical Clinic I, University Hospital, Dresden, Germany

5:00 PM
Characteristics of Transfused Platelets Do Not Affect Bleeding Outcomes in Hypoproliferative Thrombocytopenia

Darrell Triulzi, MD1, Susan Assmann, PhD2*, Ronald G. Strauss, MD3, Paul M. Ness, MD4, John R. Hess, MD, MPH5*, Suzanne Granger2* and Sherrill J. Slichter, MD6

1Institute for Transfusion Medicine, Pittsburgh, PA
2New England Research Institute, Watertown, MA
3University of Iowa Hosp., Iowa City, IA
4Johns Hopkins Hospital, Johns Hopkins Medical Institute, Baltimore, MD
5Univ. of Maryland School of Medicine, Baltimore, MD
6Puget Sound Blood Center, Seattle, WA

5:15 PM
HLA Class I Typing of Platelets by Multi-Colour Flow Cytometry - A New Powerful Tool for Assessing Survival, Activation Status and Activation Capacity of Transfused Platelets Vs. Autologous Platelets and for Determination of Stem Cell Engraftment After Allogeneic Stem Cell Transplantation

Annette Vetlesen, MT1*, Pål Andre Holme, MD, PhD2*, Torstein Lyberg, MD, PhD3* and Jens Kjeldsen-Kragh, MD, PhD1*

1Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, Norway
2Department of Internal Medicine, Division of Haematology, Oslo University Hospital, Oslo, Norway
3Center for Clinical Research, Oslo University Hospital, Oslo, Norway

5:30 PM
Collection and Storage of Apheresis Platelets Results in a Significant Decline in the Percentage of Coated-Platelets

Roseleen Charania, MBBS, MD1, James W Smith, MD, PhD2, Sara K. Vesely, PhD3, George L. Dale, PhD4 and Jennifer L. Holter, MD1

1Hem/Onc, Univ. of Oklahoma Health Sciences Center, Oklahoma City, OK
2Oklahoma Blood Institute, Oklahoma City, OK
3University of Oklahoma Health Sciences Center, Oklahoma City, OK
4University of Oklahoma, Oklahoma City, OK

5:45 PM
Characterization of the Human Neutrophil Alloantigen (HNA) 3a

Juergen Bux, MD, PhD1, Jan Wesche2*, Elke Hammer, PhD3*, Uwe Voelker, PhD3*, Angelika Reil, MD1* and Andreas Greinacher, MD4

1German Red Cross Blood Service West, Hagen, Germany
2Institute for Immunology & Transfusion, Greifswald, Germany
3Interfakultäres Institut für Genetik und Funktionelle Genomforschung, Ernst Moritz Arndt Universität, Greifswald, Germany
4Institute for Immunology & Transfusion, Ernst Moritz Arndt University, Greifswald, Germany

*signifies non-member of ASH