-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

614.P1.33 614. Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation: Poster I

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
ALL, antibodies, Biological, CRS, Leukemia, Animal models, bone marrow, Diseases, Lymphoma (any), neurotoxicity, Non-Biological, CAR-Ts, Combinations, Therapies, Adverse Events, chemotherapy, Pediatric, Biological Processes, gene therapy, immune cells, Technology and Procedures, Young Adult, Cell Lineage, immunotherapy, gene editing, infusion, Lymphoid Malignancies, Study Population, Clinically relevant, imaging, immune mechanism, inflammation, microenvironment, molecular interactions
Saturday, December 5, 2020: 7:00 AM-3:30 PM

Nicholas J. Short, MD1, Hagop M. Kantarjian, MD1, Farhad Ravandi, MBBS1, Xuelin Huang, PhD2*, Nitin Jain, MD1, Tapan M. Kadia, MD1, Joseph D. Khoury, MD3, Jeffrey L. Jorgensen, MD, PhD4*, Sa A Wang, MD4*, Yesid Alvarado, MD1, Jan A. Burger, MD, PhD1, Naval Daver, MD1, Gautam Borthakur, MD1, Courtney D. DiNardo, MD, MSc1, Marina Konopleva, MD, PhD1, Naveen Pemmaraju, MD1, Guillermo Garcia-Manero, MD1, William G. Wierda, MD, PhD1, Steven M. Kornblau, MD1, Jovitta Jacob, RN1*, Meagan Rostykus, RN1*, Monica Kwari, BSN1, Caitlin R. Rausch, PharmD5*, Christopher Loiselle, BS1*, Anna Milton1*, Juan Rivera1*, Rebecca Garris, MSc1*, Susan M. O'Brien, MD6 and Elias Jabbour, MD1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX
6UCI Cancer Center, Orange, CA

Klaudyna Fidyt, MSc1,2*, Julia Cyran1*, Agata Pastorczak3*, Nicholas T. Crump4*, Angelika Muchowicz1*, Agnieszka Goral1*, Krzysztof Domka1*, Lukasz Komorowski1,2*, Karolina Siudakowska1*, Agnieszka Graczyk-Jarzynka1*, Elzbieta Patkowska5*, Magdalena Winiarska1*, Jakub Golab1*, Thomas A. Milne4 and Malgorzata Firczuk, PhD1*

1Department of Immunology, Medical University of Warsaw, Warsaw, Poland
2Postgraduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland
3Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland
4MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, NIHR Oxford Biomedical Research Centre Haematology Theme, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
5Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland

Sara Ghorashian, FRCPath, PhD1, Caroline Furness2*, Michelle Cummins3*, John A Snowden, BSc (Hons), MBChB, MD, FRCP, FRCPath4, Maeve A O'Reilly, MBBCHBAO5, Claire Roddie, PhD, MD6*, Lorna Neill7*, Emma Nicholson8*, Caroline Besley, MBBChir, MRCPath, MRCP9*, Sridhar Chaganti, MD, PhD, MRCP, FRCPath10*, John Gillson, MD11*, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath12, Anna Castleton, FRCPath13*, Amit Patel, MBBS, PhD, FRCPath, MRCP14, Peter Clark, MA MD FRCP15*, Robert Fernley15*, Robert Wynn, MD16, Ajay Vora, MD17, David I. Marks, MB, MS, FRACP, PhD, FRCPath18, Geoff Shenton19*, Persis J Amrolia, FRCP, FRCPath, PhD20*, Denise Bonney21* and Rachael E Hough, MD22*

1Developmental Biology and Cancer, UCL Great Ormond Street Institute of Child Health, London, ENG, United Kingdom
2Haemato-Oncology, Royal Marsden NHS Foundation Trust, London, United Kingdom
3BRISTOL ROYAL HOSPITAL FOR CHILDREN, BRISTOL, GBR
4Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom
5Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
6UCL Cancer Institute, London, United Kingdom
7Department of Haematology, University College London Hospitals NHS Foundation Trust, London, ENG, United Kingdom
8Department of Haematology/ Bone marrow transplantation, The Royal Marsden NHS Foundation Trust, London, United Kingdom
9Haematology/BMT, University Hospitals Bristol, Bristol, United Kingdom
10Centre for Clinical Haematology, University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom
11Department of Haematology, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
12Haematological Medicine, King's College Hospital NHS Foundation Trust, London, United Kingdom
13Haematology, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
14Haematology and Transplant Unit, The Christie Hospital, Manchester, United Kingdom
15NHS England and NHS Improvement, Redditch, United Kingdom
16Dept. of Blood and Marrow Transplantation, Royal Manchester Children's Hospital, Manchester, United Kingdom
17Great Ormond Hospital, London, United Kingdom
18University Hospitals Bristol and Weston NHS Foundation Trust, Professor of Haematology and Stem Cell Transplantation University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom
19Newcastle Hospitals NHS Foundation, Newcastle upon Tyne, United Kingdom
20Bone Marrow Transplantation Department, Great Ormond Street hospital NHS Trust, London, United Kingdom
21Department of Blood and Marrow Transplant, Royal Manchester Children's Hospital, Manchester, United Kingdom
22Haematology, UCLH, London, United Kingdom

Yi Wang, MD1*, Hui Wang, Master1*, Ying Gao, PhD1*, Ding Zhang, Bachelor1*, Yan Zheng, MD1*, Xingxing Hu, Master1*, Qiuying Gao, Master1*, Zuohan Peng, PhD2,3*, Le Li2*, Ben Niu, Master1*, Limin Hou, Master1*, Ling Wang, Bachelor1*, Weihua Zhang, Bachelor1*, Yi Zhang, Bechelor1* and Xingli Ru, Bachelor1*

1Department of Hematology, Shaanxi Provincial People's Hospital, Xi'an, China
2Sunnycell Therapeutics Co., Ltd, Xi'an, China
3Faculty of Medicine, Northwest University, Xi'an, China

Elizabeth A. Raetz, MD1, David T. Teachey, MD2, Charles Minard, PhD3*, Xiaowei Liu, MS4*, Robin Norris, MD, MS, MPH5, Joel Reid, PhD6*, Thalia Beeles, MPh4*, Lia Gore, MD7, Elizabeth Fox, MD8*, Mignon L. Loh, MD9, Brenda J. Weigel, MD, MSc10* and William L. Carroll, MD1

1Department of Pediatrics and Perlmutter Cancer Center, NYU Langone Health, New York, NY
2Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
3Dan L. Duncan Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX
4Children's Oncology Group, Monrovia, CA
5Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
6Mayo Clinic, Rochester, MN
7Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado and Children’s Hospital, Aurora, CO
8St. Jude Children's Research Hospital, Memphis, TN
9Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of California Benioff Children’s Hospital, San Francisco, CA
10University of Minnesota, Minneapolis, MN

Shoji Saito, MD, PhD1, Ikumi Nakashima2*, Aiko Hasegawa, Ph.D.2*, Eiichi Akahoshi3*, Mitsuko Ishihara-Sugano3*, Shigeki Yagyu, MD, PhD2* and Yozo Nakazawa, MD, PhD2*

1Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, NAG, Japan
2Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
3Corporate Research & Development Center, Toshiba Corporation, Kawasaki, Japan

Lingyan Wang, PhD/DVM1*, Yue Zhang, MS1*, Eden Anderson, BS2*, Rajesh Kumar, PhD1*, Adam J. Lamble, MD3 and Rimas J Orentas, PhD1,4

1Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA
2School of Medicine, University of Washington, Seattle, WA
3Hematology-Oncology, Seattle Children's Hospital, Seattle, WA
4Pediatrics, University of Washington School of Medicine, Seattle, WA

Hind Rafei, MD1, Hagop M. Kantarjian, MD2, Koji Sasaki, MD3, Nicholas J. Short, MD4, Farhad Ravandi, MBBS5, Xuelin Huang, PhD6*, Joseph D. Khoury, MD7, Sa A Wang, MD8*, Jeffrey L. Jorgensen, MD, PhD9*, Issa F. Khouri, MD10, Partow Kebriaei, MD10, Nitin Jain, MD11, Bouthaina S. Dabaja, MD12*, Lucia Masarova, MD4*, Tapan M. Kadia, MD13, Shilpa Paul, PharmD14*, Dan Nichols15*, Guillermo Garcia-Manero, MD4, Jan A. Burger, MD, PhD4, Courtney D. DiNardo, MD, MSc16, Naval Daver, MD17, Guillermo Montalban-Bravo, MD4*, Musa Yilmaz, MD3, Prithviraj Bose, MD3, Rita Khouri18*, Philip A. Thompson, MB, MS19, Jovitta Jacob4*, Meagan Rostykus, RN4*, Rebecca Garris, MSc4*, Marina Konopleva, MD, PhD20, Susan M. O'Brien, MD21 and Elias Jabbour, MD4

1MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
6Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
8University of Texas MD Anderson Cancer Center, Department of Hematopathology, Houston, TX
9Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
10Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
11Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
12Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
13Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
14Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX
15The University of Texas MD Anderson Cancer Center, Houston
16Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
17Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
18University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, TX
19The University of Texas MD Anderson Cancer Center, Houston, TX
20Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
21UCI Cancer Center, Orange, CA

Helen Jingshu Jin1,2, Sara Rapic2*, Ruijuan He2*, Mark D. Minden1,2* and Ralph S. DaCosta1,2,3*

1Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
2Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
3Techna Institute, University Health Network, Toronto, ON, Canada

Anthony Ross, MD1, Miyoung Lee, PhD2*, Jamie Hamilton3*, Raira Ank3*, Priscilla Do, PhD3*, Jamie Story3*, Sunil S. Raikar, MD4, Erik Dreaden, PhD3*, Christopher C. Porter, MD5 and Curtis J. Henry, PhD6

1Emory University/Children's Healthcare of Atlanta, Atlanta, GA
2Emory University, Atlanta, GA
3Emory University, Atlanta
4Aflac Cancer and Blood Disorders Center, Emory University/Children's Healthcare of Atlanta, Atlanta, GA
5Department of Pediatrics, Emory University, Atlanta, GA
6Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA

Vasu Babu Goli, MD1*, Hasmukh Jain, MD, DM1,2*, Prashant Tembhare, MD3,4*, Dhanlaxmi Lalit Shetty, PhD5,6*, Avinash Bonda, MD, DM1,2*, Lingaraj Nayak, MD, DM2,7*, Nikhil Patkar, MD4,8*, Papagudi Ganesan Subramanian, MD4,9* and Manju Sengar, MD, DM1,10

1Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
2Adult Hematolymphoid Disease Management Group, Tata Memorial Centre, Mumbai, India
3Adult & Pediatric Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
4Hematopathology Laboratory, Tata Memorial Centre, Mumbai, India
5Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, ACTREC, Navi Mumbai, Maharashtra, IND
6Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
7Bone Marrow Transplant Unit, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre., Navi Mumbai., India
8Haematopathology Laboratory, Tata Memorial Hospital, Navi Mumbai, India
9Hematopathology Laboratory, ACTREC, Tata Memorial Centre, Mumbai, Maharashtra, India
10Adult Hematolymphoid Disease Management Group, Tata Memorial Centre, Mumbai, Maharashtra, India

*signifies non-member of ASH