Asher Chanan-Khan, MD¹, Paula Cramer, MD^2*, Graeme Fraser, MD FRCPC³, Rodrigo Santucci Silva, MD⁴, Sebastian Grosicki, MD, PhD⁵, Aleksander Pristupa, MD^6*, Marie Sarah Dilhuydy, MD^7*, Andre Goy, MD⁸, Anthony R. Mato, MD, MSCE⁸, Rajendra Damle, PhD⁹, Charles Phelps, MS^10*, Michelle Mahler, MD^10*, Mariya Salman, PhD^10*, Michael Schaffer, PhD^9*, Angela Howes, PhD¹¹ and Sriram Balasubramanian, PhD⁹

¹Division of Hematology, Mayo Clinic, Jacksonville, FL
²Department I of Internal Medicine, University of Cologne, Cologne, Germany
³Juravinski Cancer Centre, McMaster University, Hamilton, ON, Canada
⁴Hemomed Oncologia e Hematologia, IEP São Lucas, São Paulo, Brazil
⁵Silesian Medical University, Katowice, Poland
⁶Regional Clinical Hospital, Ryazan, Russia
⁷Hôpital Haut-Lévêque, Pessac, France
⁸John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
⁹Janssen Research & Development, Springhouse, PA
¹⁰Janssen Research & Development, Raritan, NJ
¹¹Janssen Research & Development, High Wycombe, United Kingdom

Valentin Goede, MD^1*, Kirsten Fischer, MD^2*, Francesc Bosch³, George Follows^4*, Henrik Frederiksen^5*, Antonio Cuneo^6*, Heinz Ludwig⁷, Noelle Crompton^8*, Joerg Maurer^9*, Marianne Uguen^9*, Gunter Fingerle-Rowson⁹ and Michael Hallek, MD¹

¹German CLL Study Group, Department I of Internal Medicine, Center of Integrated Oncology Cologne-Bonn, University Hospital Cologne, Cologne, Germany
²Department I of Internal Medicine, Center of Integrated Oncology Cologne-Bonn, University Hospital Cologne, Cologne, Germany
³Department of Hematology, University Hospital Vall d’Hebron, Barcelona, Spain
⁴Department of Haematology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
⁵Hematology Department, Odense University Hospital, Odense, Denmark
⁶Hematology Section, Azienda Ospedaliero Universitaria Arcispedale S. Anna, University of Ferrara, Ferrara, Italy
⁷Department of Medicine I, Wilhelminenhospital, Vienna, Austria
⁸F. Hoffmann-La Roche Ltd, Welwyn Garden City, United Kingdom
⁹F. Hoffmann-La Roche Ltd, Basel, Switzerland

Jeanette Lundin, MD, PhD^1*, Steven T. Rosen, MD², Anders Österborg, MD PhD¹, Olga Frankfurt, MD³, Jane N. Winter, MD⁴, Alfred Rademaker^5*, Jennifer Kreutzer^5*, Elizabeth Bacon^5*, Sonja Sönnert-Husa^6* and Shuo Ma, MD, PhD⁷

¹Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
²Division of Hematopoietic Stem Cell and Leukemia Research of Beckman Research Institute, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA
³Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
⁴Department of Medicine-Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL
⁵Northwestern University, Chicago, IL
⁶Karolinska University Hospital, Stockholm, Sweden
⁷Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL

Tiago R Matos, MD, MSc^1,2*, Benjamin L Lampson, MD, PhD^3*, Masahiro Hirakawa, MD, PhD^1*, Siddha Kasar, PhD^3*, Stacey M. Fernandes^3*, Jennifer R. Brown, MD, PhD⁴ and Jerome Ritz, MD⁵

¹Division of Hematologic Malignancies and Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²Faculdade de Medicina da Universidade de Lisboa, Instituto de Medicina Molecular, Lisbon, Portugal
³Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁴Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
⁵Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA

Michael Y. Choi, M.D.¹, George F. Widhopf II, PhD¹, Januario Castro, MD¹, Hongying Li, PhD^1*, Reilly L Kidwell, BS, BA, CCRC^1*, Sam C Zhang, B.A.^1*, Tiffany Juarez, PhD^1,2*, Susette Gorak^1*, Laura Z. Rassenti, PhD¹, Karen Messer, PhD^1*, Charles Prussak, PhD¹, Catriona HM Jamieson, MD, PhD^1,2 and Thomas J. Kipps, MD, PhD³

¹Moores Cancer Center, University of California, San Diego, La Jolla, CA
²Division of Regenerative Medicine, University of California, San Diego, La Jolla, CA
³University of California, San Diego, La Jolla, CA

Kayo Kondo, PhD^1*, Jan A. Burger, MD, PhD², Keating Micheal, MD^2*, Jamie Tran^1*, Muharrem Muftuoglu^1*, May Daher^3*, Hila Shaim, MD^1*, Philip Thompson, MBBS^2*, Nobuhiko Imahashi, MD, PhD^1*, Abdullah Alsuliman^1*, William Wierda, MD, PhD⁴, Enli Liu, MD, MS^1*, Elizabeth J. Shpall, MD¹ and Katayoun Rezvani, MD PhD¹

¹Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Benedetta Apollonio, PhD^1*, Mariam Fanous, BSc, MSc^1*, Mohamed-Reda Benmebarek, BSc, MRes^1*, Stephen Devereux, FRCP, FRCPath, PhD², Patrick Hagner, PhD^3*, Michael Pourdehnad, MD^4*, Anita K. Gandhi, PhD^3*, Piers E. Patten, BSc, MRCP, MRCPath, PhD² and Alan G. Ramsay, PhD¹

¹Department of Haemato-Oncology, King’s College London, London, United Kingdom
²Haematology, King's College Hospital, London, United Kingdom
³Celgene Corporation, Summit, NJ
⁴Celgene Corporation, San Francisco, CA

Carolina Pavlovsky, MD^1*, Isolda Fernandez, MD^2*, Miguel A Pavlovsky, MD³, Adriana Galeano^2*, Federico Sackmann^2*, Dante Intile, Statistic^2* and Astrid Pavlovsky, MD^4*

¹FUNDALEU, Buenos Aires, Argentina, Buenos Aires, Argentina
²FUNDALEU, Buenos Aires, Argentina
³Fundaleu / Centro Hematológico Pavlovsky, Buenos Aires, Argentina
⁴Fundaleu, Buenos Aires, Argentina

Caspar da Cunha-Bang^1*, Jacob Simonsen^2*, Klaus Rostgaard^2*, Christian H Geisler³, Henrik Hjalgrim^2,3* and Carsten Niemann³

¹Department of Internal Medicine, Roskilde Hospital, Roskilde, Denmark
²Department of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark
³Department of Hematology, Rigshospitalet, Copenhagen, Denmark

Jian Yu, PhD^1*, Liguang Chen, MD, PhD^1*, George F. Widhopf II, PhD¹, Suping Zhang, PhD^1*, Bing Cui, PhD^1*, Rongrong Wu, PhD^1*, Ling Zhang, PhD^1* and Thomas J. Kipps, M.D., PhD.^1,2

¹Moores Cancer Center, University of California, San Diego, La Jolla, CA
²CLL Research Consortium, La Jolla, CA

Christine I Chen, MD¹, Susi Snitzler, RN^1*, Olga Levina, RN^1*, Tong (Trina) Wang, RN^1*, Lisa W Le, MSc^2*, Harminder Paul^1*, Ellen Nong Wei^1*, Anthea Lau^2*, Michelle Queau^3*, James B Johnston, MD³, Suzanne Trudel, MD¹ and Deborah A Smith^4*

¹Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
²Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada
³Manitoba Institute of Cell Biology, Cancer Care Manitoba, Winnipeg, MB, Canada
⁴GlaxoSmithKline, Mississauga, Canada

Chi-Ling Chiang^1*, Frank W Frissora^1*, Zhiliang Xie^1*, Xiaomeng Huang^2*, Rajeswaran Mani, DVM^3*, Sivasubramanian Baskar^4*, Christoph Rader^5*, Kenneth K. Chan^6*, Guido Marcucci, MD⁷, John C. Byrd, MD⁸, L. James Lee^9* and Natarajan Muthusamy, DVM, Ph.D.⁸

¹The Ohio State University Comprehensive Cancer Center, Columbus, OH
²University of Utah, Salt Lake City, UT
³The Ohio State University, Columbus, OH
⁴National Cancer Institute, Bethesda, MD
⁵Department of Cancer Biology and Department of Molecular Therapeutics, Jupiter, FL
⁶Department of Pharmaceutics and Pharmaceutical Chemistry, The Ohio State University,, Columbus, OH
⁷Dept. of Hematology/ Oncology, The Ohio State Univ. Med. Ctr., Columbus, OH
⁸Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
⁹Chemical and Biomolecular Engineering Department, The Ohio State University,, Columbus, OH

Jeff P. Sharman, MD¹, Andrei R. Shustov, MD², Mitchell R. Smith, MD, PhD³, Thomas E. Boyd, MD^4*, Christopher Hagenstad, MD⁵, Kathryn S. Kolibaba, MD⁶, Steve Abella, MD^7*, Jing He^8*, Clarence Eng, MPH^7*, Jing Hu, PhD^7*, Anita Reddy, PhD^8*, Siddhartha Mitra, MD, PhD^8*, Christopher A. Yasenchak, MD⁹ and Farrukh T. Awan, MD, MS¹⁰

¹Willamette Valley Cancer Institute, Springfield, OR
²Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA
³Case Comprehensive Cancer Center, Cleveland, OH
⁴Yakima Valley Memorial Hospital, Yakima, WA
⁵Suburban Hematology-Oncology Associates, Gwinnett Hospital System, Lawrenceville, GA
⁶Compass Oncology/US Oncology Research, Vancouver, WA
⁷Gilead Sciences, Inc., Foster City, CA
⁸Gilead Sciences, Inc, Foster City, CA
⁹Willamette Valley Cancer Institute and Research Center/US Oncology Research, Springfield, OR
¹⁰Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH

Lotta Hansson, MD, PhD^1*, Maria Winqvist, MD^1*, Anna Asklid, MD^2*, P-O Andersson, MD PhD^3*, Karin Karlsson, MD^4*, Claes Karlsson, MD PhD^1*, Birgitta Lauri, MD^5*, Jeanette Lundin, MD, PhD^6*, Mattias Mattsson, MD^7*, Stefan Norin, MD PhD^1*, Anna Sandstedt, MD^8* and Anders Österborg, MD PhD⁶

¹Department of Hematology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
²Department of Oncology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
³Department of Hematology, Borås Hospital, Borås, Sweden
⁴Department of Hematology, Lund University Hospital, Lund, Sweden
⁵Department of Hematology, Sunderbyn Hospital, Sunderbyn-Luleå, Sweden
⁶Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
⁷Department of Hematology, Uppsala University Hospital, Uppsala, Sweden
⁸Department of Hematology, Linköping University Hospital, Linköping, Sweden

Edward Smith, MSc^1*, Angelo Agathanggelou, PhD^1*, Guy Pratt, MD PhD¹, Paul Moss¹, Wenbin Wei, PhD^1*, Leanine Harrigan^2*, Xavier Jacq, PhD^2* and Tatjana Stankovic¹

¹School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
²Mission Therapeutics, Cambridge, United Kingdom

Susan O'Brien, MD^1*, Andrew John Davies, BM, PhD^2*, Ian W. Flinn, MD, PhD³, Ajay K Gopal, MD⁴, Thomas J. Kipps, M.D., PhD.⁵, Gilles A. Salles, MD, PhD⁶, Terry Newcomb, PhD^7*, Christopher C. Waldapfel^7*, Zhihai Zhang^7* and Stephan Stilgenbauer, MD PhD⁸

¹University of California, Irvine/Chao Family Comprehensive Cancer Center, Orange, CA
²Cancer Sciences Unit, University of Southampton, Salisbury, United Kingdom
³Hematologic Malignancies Research Program, Sarah Cannon Research Institute, Nashville, TN
⁴Division of Medical Oncology, University of Washington, Seattle, WA
⁵Moores Cancer Center, University of California, San Diego, La Jolla, CA
⁶Hospices Civils de Lyon, University Claude Bernard, Pierre-Benite, France
⁷Gilead Sciences, Inc., Foster City, CA
⁸University of Ulm, Ulm, Germany

Candida Vitale, MD^1*, Lorenzo Falchi, MD¹, Elisa ten Hacken, PhD^1*, Hui Gao, PhD^2*, Hila Shaim, MD^3*, Katrien Van Roosbroeck, PhD^4*, George Calin, MD PhD⁴, Susan O'Brien, MD¹, Stefan Faderl, MD¹, Xuemei Wang, MS^5*, William Wierda, MD, PhD⁶, Katayoun Rezvani, MD PhD³, James M Reuben, PhD², Jan A. Burger, MD, PhD¹, Michael Keating, MBBS¹ and Alessandra Ferrajoli, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Randall Jones, B.A.^1*, Mark Joseph Axelrod, Ph.D^1*, Daniel Tumas, PhD, DVM^2*, Christophe Quéva, Ph.D.^2* and Julie Di Paolo, PhD^3*

¹Gilead Sciences, Seattle, WA
²Gilead Sciences, Foster City, CA
³Gilead Sciences, Inc., Foster City, CA

Inhye Ahn, MD¹, Mohammed Farooqui, DO², Yuh Shan Lee^2*, Gerald Marti^2*, Susan Soto, RN^2*, Xin Tian, PhD^3*, Maryalice Stetler-Stevenson^4*, Constance M. Yuan, MD, PhD^5*, Irina Maric, MD⁶ and Adrian Wiestner, MD, PhD²

¹National Cancer Institute, National Institutes of Health, Bethesda, MD
²Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
³Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
⁴Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁵Laboratory of Pathology, National Cancer Institute, Bethesda, MD
⁶Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD

Anders Österborg, MD, PhD¹, Anna Asklid, MD^2*, Joris Diels^3*, Johanna Repits, PhD^4*, Frans Söltoft, MSc^5*, Lotta Hansson, MD, PhD^1* and Ulrich Jäger, MD, PhD^6*

¹Department of Hematology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
²Department of Oncology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
³Janssen EU HEMAR Statistics & Modeling, Beerse, Belgium
⁴Nordics team, Janssen Cilag, Stockholm, Sweden
⁵Nordic HEMAR manager, Janssen Cilag, Stockholm, Sweden
⁶Medical University of Vienna, Vienna, Austria

Cody Paiva, BS^1*, Claire Godbersen^2*, Stephen E Spurgeon, MD³, Sreesha Srinivasa^4*, Jennifer R Brown, MD, PhD⁵ and Alexey V Danilov, M.D. Ph.D.¹

¹OHSU Knight Cancer Institute, Portland, OR
²Dartmouth College, Lebanon, NH
³Center for Hematologic Malignancies, Oregon Health & Science University, Portland, OR
⁴Piramal Healthcare, Mumbai, India
⁵Dana-Farber Cancer Inst., Boston, MA

Shih-Shih Chen, PhD¹, Steven Ham^1*, Kanti R. Rai, MD^1,2, Karen McGovern, PhD^3*, Jeffery L. Kutok, MD, PhD³ and Nicholas Chiorazzi, MD.^1,4

¹The Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, NY
²Department of Medicine, Hofstra North Shore - LIJ School of Medicine, Hempstead, NY
³Infinity Pharmaceuticals, Inc., Cambridge, MA
⁴The Karches Center for CLL Research, The Feinstein Institute for Medical Research, Manhasset, NY