Jieyu Wang, MD^1,2*, Yoshihiro Hayashi, MD, PhD¹, Zefeng Xu, MD^1,3, Lingyun Wu, MD, PhD^1,4*, Xiaomei Yan, MD, PhD^1*, Theodosia A. Kalfa, MD, PhD⁵, Zhijian Xiao, MD^3* and Gang Huang, PhD¹

¹Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
²Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China
³State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁴Department of Hematology, The Sixth Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China
⁵Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Danitza Nebor, PhD^1*, Raymond F. Robledo, PhD^1*, Joel H. Graber, PhD^1*, Omorose Aighewi^1*, Lionel Blanc, PhD², Andrew C Perkins³, Kevin R. Gillinder, PhD^4*, James J. Bieker, PhD⁵ and Luanne L. Peters, PhD¹

¹The Jackson Laboratory, Bar Harbor, ME
²The Feinstein Institute for Medical Research, Manhasset, NY
³Univeristy of Queensland, Woolloongabba, Australia
⁴Mater Research, University of Queensland, Woolloongabba, Australia
⁵Mount Sinai School of Medicine, New York, NY

Minyoung Youn, PhD^1*, Elena Bibikova, PhD^1*, Corinne LaVasseur, BA^1*, Bertil Glader, MD, PhD², Kathleen Sakamoto, MD, PhD^2* and Anupama Narla, MD²

¹Stanford University School of Medicine, Stanford, CA
²Division of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA

Hiromi Ogura, MD, PhD^1*, Shouichi Ohga, MD. PhD^2*, Takako Aoki, MLS^1*, Taiju Utsugisawa, MD, PhD^1*, Hidehiro Takahashi, MD PhD^3*, Asayuki Iwai^4*, Kenichiro Watanabe, MD, PhD^5*, Yusuke Okuno, MD, Ph.D.^6*, Kenichi Yoshida, MD, Ph.D.^7*, Satoru Miyano, MD, Ph.D.^8*, Seishi Ogawa, MD, Ph.D.⁹, Seiji Kojima, MD, PhD^6* and Hitoshi Kanno, MD, PhD^1,10*

¹Dept. Transfusion Medicine and Cell Processing, Tokyo Women's Medical University, Tokyo, Japan
²Department of Pediatrics, Yamaguchi University, Ube, Japan
³Department of Neonatology, Musashino Red Cross Hospital, Musashino, Japan
⁴Shikoku Medical Center for Children and Adults, Zentsuji, Japan
⁵Shizuoka Children's Hospital, Shizuoka, Japan
⁶Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
⁷Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
⁸Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
⁹Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan, Kyoto, Japan
¹⁰Division of Genomic Medicine, Department of Advanced Biomedical Engineering and Science, Graduate School of Medicine, Tokyo Women's Medical University, Tokyo, Japan

Rami Khoriaty, MD¹, Lesley Everett, BS, MPhil², Jennifer Chase^3*, Guojing Zhu^4*, Bin Zhang, PhD^5*, Mark Hoenerhoff, DVM, PhD, DACVP^6*, Ivan Maillard, MD, PhD⁷ and David Ginsburg, MD⁸

¹Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan, Ann Arbor, MI
²Department of Human Genetics and Medical Scientist Training Program, University of Michigan, Ann Arbor, MI
³Life Sciences Institute, University of Michigan, Ann Arbor
⁴Life Sciences Institute, University of Michigan, Ann Arbor, MI
⁵Cleveland Clinic, Lerner Research Institute, Cleveland, OH
⁶Unit for Laboratory Animal Meicine, University of Michigan, Ann Arbor, MI
⁷Life Sciences Institute, Center for Stem Cell Biology, University of Michigan, Ann Arbor, MI
⁸Departments of Human Genetics and Internal Medicine, University of Michigan, Howard Hughes Medical Institute, Ann Arbor, MI

Adelina Sergueeva, MD^1*, Galina Miasnikova, MD^2*, Ekaterina Lisina, MD^3*, Mehdi Nouraie, MD, PhD⁴, Sergei A. Nekhai, PhD⁵, Tatiana Ammosova, PhD^5*, Josef T. Prchal, M.D.⁶, Xu Zhang, PhD^7* and Victor R. Gordeuk, MD⁷

¹Cheboksary Children's Hospital, Cheboksary, Russia
²Chuvash Republic Clinical Hospital, Cheboksary, Russia
³Northwestern Federal Medical Research Center, St. Petersburg, Russia
⁴Center For Sickle Cell Disease, Howard University, Washington, DC
⁵Center for Sickle Cell Disease, Howard University, Washington, DC
⁶Division of Hematology, University of Utah, Salt Lake City, UT
⁷Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of Medicine, University of Illinois at Chicago, Chicago, IL

MinJung Kim, PhD^1*, Tami J. Kingsbury, PhD^1*, Wen-Chih Cheng, PhD^1*, Yee Sun Tan, PhD^1*, Brittany M. Taylor^1*, Sampada Koshatwar^2* and Curt I. Civin, MD³

¹Center for Stem Cell Biology & Regenerative Medicine and Departments of Pediatrics and Physiology, University of Maryland School of Medicine, Baltimore, MD
²Fischell Department of Bioengineering, University of Maryland, College Park, Baltimore, MD
³Center for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD

Sarah Ducamp, PhD^1,2*, Emilie-Fleur Gautier, PhD^1,2*, Marjorie Leduc^3*, Virginie Salnot^3*, Michael Dussiot, PhD^1*, François Guillonneau^3*, Marie-Catherine Giarratana^4*, Luc Douay, MD, PhD⁵, Catherine Lacombe, MD, PhD⁶, Frederique Verdier, PhD^1,2*, Yael Zermati, PhD^1,2* and Patrick Mayeux, PhD^2,3,7

¹Laboratoire d’Excellence GR-Ex, PARIS, France
²INSTITUT COCHIN, INSERM U1016, PARIS, France
³Plateforme de Protéomique 3p5, Université Paris Descartes, PARIS, France
⁴UMR_S938 CDR Saint-Antoine, Université UPMC, PARIS, France
⁵Hopital Saint-Antoine, Paris, France
⁶Institut Cochin, INSERM U1016, Paris, France
⁷Laboratoire d'excellence Gr-Ex, Paris, France

Alonso Ricardo, PhD^1*, Michelle Arata, MS^1*, Steven DeMarco, PhD^1*, Ketki Dhamnaskar, MS^1*, Robert Hammer, PhD^1*, Masha Fridkis-Hareli, PhD^2*, Vaishnavi Rajagopal, PhD^1*, Kathleen Seyb, PhD^1*, Guo-Qing Tang, PhD^1*, Sylvia Tobe, PhD^1* and Douglas Treco, PhD^1*

¹Ra Pharmaceuticals, Cambridge, MA
²ATR, LLC, Worcester, MA

Ferras Alashkar, MD^1*, Ali Canbay, MD^2*, Dörte Herich-Terhürne^1*, Ulrich Dührsen, MD³, Frank Lammert, MD^4* and Alexander Röth, MD¹

¹Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
²Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
³Department of Haematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⁴Department of Medicine II, Saarland University Hospital, Homburg, Germany

Satheesh Chonat, MD¹, Mary Risinger^2*, Neha Dagaonkar^3*, Tamara Maghathe^1*, Jennifer Rothman, MD⁴, Jessica Connor^3*, Karen Kalinyak, MD^1*, Amber H Begtrup, PhD^3*, Kejian Zhang, MD, MBA^3* and Theodosia A. Kalfa, MD, PhD¹

¹Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²College of Nursing, University of Cincinnati, Cincinnati, OH
³Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁴Duke University Medical Center, Durham, NC

Paola Bianchi, PhD^1*, Anna Zaninoni, BSc, PhD^1*, Elisa Fermo, PhD^1*, Cristina Vercellati, BSc^1*, Marcello Anna Paola, BSc^1*, Alberto Zanella, M.D.¹, Agostino Cortelezzi, MD² and Wilma Barcellini, MD^3*

¹Oncohematology Unit - Physiopathology of Anemias Unit, Foundation IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy
²Oncohematology Unit, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
³Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy

Yamaja B. Setty, PhD^1*, Suhita Gayennebetal^2*, Nigel S. Key, MB, ChB³ and Marie Stuart, MD^1*

¹Nemours Center for Cancer and Blood Disorders, A I DuPont Hospital for Children, Wilmington, DE
²Neonatology Research Lab, A I DuPont Hospital for Children, Wilmington, DE
³Division of Hematology/Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC

Kanuri Giridhar, PhD^1*, Sawhney Ritica, M. Sc^1*, Chichula Deepti, M. S^1* and Arun S Shet, MD^1,2

¹Wellcome Trust- DBT Hematology Research Division, St. Johns Research Institute, Bangalore, India
²Department of Hematology & Medical Oncology, St. John’s Medical College & Hospital, Bangalore, India

Leo Kager, MD^1*, Lesley J Bruce, PhD^2*, Joanna F Flatt, PhD^2*, Petra Zeitlhofer, MD^3*, Gerhard Fritsch, PhD^1*, Bernhard Fahrner, MD^1* and Oskar A. Haas^1,3

¹St. Anna Children's Hospital, Childrens Cancer Research Institute, Vienna, Austria
²Bristol Institute for Transfusion Sciences, NHS Blood and Transplant, Bristol, United Kingdom
³medgen.at GmbH, Vienna, Austria

Frances Smith^1*, David Brawand^1*, Laura Steedman^1*, Matthew Oakley^1*, Christopher Wall^1*, Peter Rushton^1*, Margaret Allchurch^2*, Keith Sibson^3*, Claire Jane Hemmaway, MD^4*, Swee Lay Thein, MD, DSc^5,6, David C. Rees, FRCP, FRCPath, MA, MBBS^7* and Barnaby E. Clark, Ph.D.^1,6*

¹Department of Molecular Pathology, Viapath at King's College Hospital, London, United Kingdom
²Haematology, Queen's Hospital, Romford, United Kingdom
³Great Ormond Street Hospital, London, United Kingdom
⁴ba, Romford, United Kingdom
⁵National Heart, Lung and Blood Institute, Sickle Cell Branch, National Institutes of Health, Bethesda, MD
⁶Molecular Haematology, Division of Cancer Studies, King's College London, London, United Kingdom
⁷King's College Hospital, London, United Kingdom