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Thrombus Formation

Tuesday, December 9, 2008: 1:00 PM-2:30 PM
309 - South (Moscone Center)
Moderators:
Ali Amirkhosravi and Erin Zekas, B.S.
1:00 PM
2857
Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Ali Amirkhosravi, Ph.D.1*, Todd V Meyer, Ph.D.1*, Liza Robles-Carillo, MS1*, Monica Davila, Ph.D.1*, Florian Langer, MD2*, Hina Desai, MS1*, Patricia Weinstein, RN3*, Mildred Amaya, MS1*, Eduardo Reyes, MS1* and John L Francis, Ph.D.1

1Center for Thrombosis Research, Florida Hospital, Orlando, FL
2Hematology and Oncology, University Hospital Eppendorf, Hamburg, Germany
3College of Nursing, University of Central Florida, Orlando, FL
1:15 PM
2014
Fluorescence Resonance Energy Transfer Studies of Prothrombin Recognition by Prothrombinase

Erin Zekas, B.S.* and Sriram Krishnaswamy, PhD

Children's Hospital of Philadelphia, Philadelphia, PA
1:30 PM
2022
Effects of Substrate Geometry on Active Site Engagement Govern the Preferential Action of Prothrombinase on One of the Two Cleavage Sites in Prothrombin

Harlan N Bradford, B.S.*, Joseph A Micucci, B.S.* and Sriram Krishnaswamy, PhD

Children's Hospital of Philadelphia, Philadelphia, PA
1:45 PM
1022
The Nature of LPS-Stimulated Monocyte Tissue Factor Activity

Saulius Butenas, PhD*, Behnaz Parhami-Seren, PhD*, Matthew T. Gissel*, Jolanta Amblo*, Kathleen E. Brummel-Ziedins, PhD* and Kenneth G. Mann, PhD

Biochemistry, University of Vermont, Colchester, VT
2:00 PM
1020
The Effect of Factor Va on Prothrombinase Function

Michael Kalafatis, PhD, Jamila Hirbawi, BS*, Melissa A. Barhoover, PhD* and Michael A. Bukys, PhD*

Cleveland State University, Cleveland, OH
2:15 PM
2012
The Regulatory Function of Amino Acid Region 659-663 of Factor Va on Prothrombinase during Thrombin Formation

Jamila Hirbawi* and Michael Kalafatis*

Cleveland State University, Cleveland, OH
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