50th ASH Annual Meeting and Exposition (December 6 - 9, 2008): Hematopoiesis - Regulation of Gene Transcription Poster II

Sunday, December 7, 2008: 6:00 PM-8:00 PM

Hall A (Moscone Center)

Functional analysis of the Human Pbx Interacting Protein (HPIP) in Human Hematopoiesis

Pawandeep Kaur, M.Sc, (Hons)¹^*, Christiane Stadler, PhD¹^*, Farid Ahmed, PhD¹^*, Monica Cusan, MTA¹^*, R. Keith Humphries, MD, PhD², Wolfgang Hiddemann, MD³, Christian Buske, PD, med¹^* and Michaela Feuring-Buske, PD, med¹^*

¹Haematologikum, Klinische Kooperationsgruppe am Hämatologikum der Helmholtz Zentrum, Medizinische Klinik III, Klinikum der LMU München-Großhade, Muenchen, Germany
²Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada
³Department of Internal Medicine III, University of Munich-Hopsital Großhadern, Munich, Germany

2431

The Histone Acetyl-Transferase MOZ Cooperates with the Histone Methyl-Transferase MLL to Regulate HOX Gene Expression in Human Hematopoietic Stem Cells

Jérôme Paggetti^*, Romain Aucagne^*, Arnaud Jacquel, PhD^*, Anne Largeot^*, Brice Lagrange^*, Eric Solary, MD, Jean-Noël Bastie, MD, PhD^* and Laurent Delva, PhD^*

Faculté de Médecine, Université de Bourgogne, Inserm U866, Dijon, France

2432

Local and Distant Elements Regulate Tissue-Specific Expression of ANK-1 Gene Transcripts

Ashley N. Owen¹^*, Karina Laflamme, PhD¹^*, Andre M. Pilon, MS¹^*, Lisa J. Garrett, MS²^*, Patrick G. Gallagher, MD³ and David M. Bodine, PhD¹

¹Nhgri, Hematopoiesis Section, GMBB, Bethesda, MD
²Nhgri, Transgenic Mouse Core Facility, Bethesda, MD
³School of Medicine, Yale University, New Haven, CT

2433

Wnt/β-Catenin Pathway Affects the Cell-Fate Decisions of Hematopoietic Stem/Progenitor Cells Modulating the Epigenetic States of Various Essential Transcription Factors

Hirokazu Tanaka, M.D., Ph.D.¹^*, Itaru Matsumura, M.D., Ph.D.¹^*, Yusuke Satoh, M.D., Ph.D.¹^*, Sachiko Ezoe, M.D., Ph.D.¹^*, Tatsutoshi Nakahata, M.D., Ph.D.²^* and Yuzuru Kanakura, M.D., Ph.D.¹^*

¹Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Japan
²Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan

2434

Integrated Biochemical and Computational Approach Identifies BCL6 Direct Target Genes Controlling Multiple Pathways in Normal Germinal-Center B Cells

Masumichi Saito, PhD¹^*, Katia Basso, PhD¹^*, Pavel Sumazin, PhD²^*, Adam A Margolin, PhD²^*, Kai Wang, PhD²^*, Wei-Keat Lim²^*, Andrea Califano, PhD³^* and Riccardo Dalla-Favera, MD⁴

¹Institute for Cancer Genetics, Columbia University, New York, NY
²Joint Centers for Systems Biology, Columbia University, New York, NY
³Department of Biomedical Informatics and Joint Centers for Systems Biology, Columbia University, New York, NY
⁴Institute for Cancer Genetics, Department of Pathology and Genetics & Development, Columbia University, New York, NY

2435

HIF-1 Prevents Hematopoietic Cells from Cell Damage by Overproduction of Mitochondrial ROS after Cytokine Stimulation through Induction of PDK-1

Keita Kirito, MD¹, Kozue Yoshida²^*, Yongzhen Hu³^*, Qiao Qiao¹^*, Kumi Sakoe¹^* and Norio Komatsu¹^*

¹Dept. of Hematology, University of Yamanashi, Chuo, Japan
²Medicine, Jichi Medical School, Shimotsuke, Japan
³Hematology, Guangdong Provincial Hospital of TCM, China

2436

Chromatin Architecture and Transcription Factor Occupancy of Erythrocyte Membrane Genes Studied by Chromatin Immunoprecipitation on Microarrays (ChIP-chip)

Laurie A Steiner¹^*, Yelena Maksimova¹^*, Clara Wong¹^*, Vincent Schulz²^* and Patrick G. Gallagher, MD³

¹Pediatrics, Yale University School of Medicine, New Haven, CT
²Ycemh, Yale University, New Haven
³School of Medicine, Yale University, New Haven, CT

2437

Single-Stranded DNA-Binding Proteins (SSBPs) Promote the Oligomerization of LIM-Domain Binding Protein Ldb1

Ying Cai, PhD¹^*, Lalitha Nagarajan, PhD²^* and Stephen J. Brandt, MD³

¹Div. of Hematology-Oncology, Vanderbilt Univ. Medical Ctr., Nashville, TN
²Dept. of Molecular Genetics, UT-MD Anderson Cancer Ctr., Houston, TX
³Vanderbilt Univ. Medical Ctr., Nashville, TN

2438

The MiR23A MicroRNA Cluster Is a Target of PU.1 and Promotes Development of Myeloid Cells at the Expense of B Cells

Kristin S Owens, BA¹^*, Kimi Y Kong, PhD¹^*, Jason H Rogers, BS¹^* and Richard E. Dahl, PhD²

¹Cancer Research and Treatment Center, University of New Mexico, Albuquerque, NM
²Univ. of New Mexico Health Sciences Ctr., Albuquerque, NM

2439

Identification of Gfi1 as a Direct Target of the Leukemogenic Fusion Protein AML1-ETO9a

Miao-Chia Lo¹^*, Luke F. Peterson²^*, I-Ming Chen³, Cheryl L. Willman³ and Dong-Er Zhang¹

¹Moores Cancer Center, University of California San Diego, La Jolla, CA
²Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI
³University of New Mexico Cancer Research and Treatment Center, Albuquerque, NM

2440

Frequent in Vivo redundancy of C/EBPß and C/EBPε during Myeloid Development

Nils Heinrich Thoennissen¹^*, Tadayuki Akagi¹^*, Sam Abbassi¹^*, Daniel Nowak¹^*, Ann George²^*, Gay M. Crooks, MD², C. Müller-Tidow, MD³^*, Adrian F Gombart¹^* and Phillip H Koeffler¹^*

¹Division of Hematology and Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA
²Children's Hospital, Los Angeles, CA
³University Hospital, Münster, Germany

See more of: Oral and Poster Abstracts

<< Previous Session | Next Session >>

^*signifies non-member of ASH