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Basic Science and Clinical Practice in Blood Transfusion Poster II

Sunday, December 7, 2008: 6:00 PM-8:00 PM
Hall A (Moscone Center)
Sym001, the First Recombinant Polyclonal Rhesus-D Specific Antibody Product, Was Safe and Well-Tolerated in a Placebo-Controlled Randomized Phase I Trial

Peter Hjelmström, MD, PhD1*, Bengt Hallén, PhD1*, Ewa Lindenstroem, MD, PhD2 and Shwe Gyaw, MD3*

1Biovitrum AB, Stockholm, Sweden
2Symphogen A/S, Lyngby, Denmark
3Parexel, Baltimore, MD

Pharmacokinetics, Clinical Efficacy and Safety of Plasma-Derived Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary and Acquired Angioedema

J. J. Hofstra, MD1*, E. van Twuyver, PhD2*, I. Kleine-Budde, PhD2*, C. W. Choi, MD, PhD1*, M. Levi, Prof, MD, PhD1*, F. W.G. Leebeek, MD, PhD3, J. G.R. de Monchy, Prof, MD, PhD4*, P. F. Ypma, MD, PhD5*, A. D. Huitema, PhD6*, A. Nienhuis7* and P. F. Strengers, PhD2*

1Department of Internal Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands
2Medical Department, Sanquin, Amsterdam, Netherlands
3Department of Hematology, Erasmus Medical Center, Rotterdam, Netherlands
4Department of Allergology, University Medical Centre Groningen, Groningen
5Department of Hematology, HAGA Hospital, The Hague
6Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam
7Nienhuis Medstat, Schoorl

Post-Release Breakage Rate of Cryopreserved Cord Blood Products (CB) Shipped to 135 Transplant Centers from a Single Cord Blood Bank

Ping Law, PhD, Brian Wang, MS*, Laura Gindy*, Matt McCarter*, Jerry Hernandez*, Rafael Bolanos*, Susanna Hwee*, Joshua Chen*, Albert Chen*, Matt Lew*, Tiffany Chow*, Lawrence Petz, MD* and Robert Chow, MD, AM

StemCyte International Cord Blood Center, Covina, CA

High Sensitivity Detection of Bacillus Cereus in Plasma Samples

Shilpakala Sainath Rao, Ph.D.*, Ketha V. K. Mohan, Ph.D.* and Chintamani D Atreya, Ph.D.*

Division of Hematology, Center for Biologics Evaluation & Research, FDA, Bethesda, MD

Potential Use of miRNAs as Platelet Biomarkers of Storage

Meganathan Kannan, Ph.D.*, Ketha V. K. Mohan, Ph.D.*, Sandhya Kulkarni, M.S.* and Chintamani D Atreya, Ph.D.*

Division of Hematology, Center for Biologics Evaluation and Research, FDA, Bethesda, MD

Generation of Blood Cells from Human Ips Cells in Vitro through the Hematopoietic Progenitors Concentrated within the Unique Structures, Ips-Sac

Naoya Takayama1*, Koji Eto1, Hiromitsu Nakauchi1* and Shinya Yamanaka2*

1Division of Stem Cell Therapy, Center for Stem Cell and Regenerative Medicine, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
2Department of Stem Cell Biology, Center for iPS Cell Research and Application iCeMS, Kyoto University, Kyoto, Japan

Pathogen Inactivation of Platelet Concentrates by UVC-Light: Influence on Platelet Quality, Vitality, Membrane Integrity and Mitochondrial Function

Walter Nussbaumer, MD1, Harald Schennach1*, Eva-MAria Amann1*, Oliver Nussbaumer1*, Werner Streif2*, Christian Reif2*, Martin Hermann3* and Paul Hengster3*

1Dept. of Transfusion Medicine, Univ. Hospital Innsbruck, Innsbruck, Austria
2Dept. of Paediatrics, Univ. Hospital Innsbruck, Innsbruck, Austria
3Dept. of Visceral-, transplant- and Thoracic Surgery, Univ. Hospital Innsbruck, Innsbruck, Austria

Photochemical Pathogen Inactivation Treatment of Human Plasma (amotosalen + UVA) Has No Major Impact on the Protein expression pattern Assessed by a 2-DIGE Proteomic Assay

Jean-Pierre Cazenave, MD, PhD1, Philippe Ohlmann1*, Hervé Isola2* and Christian Gachet, MD1

1EFS-Alsace, UMR_S311, Université Louis Pasteur, Strasbourg, France
2EFS-Alsace, UMR_S311, Université Louis Pasteur

Platelets in Storage:  Altered S-Nitrosothiol Metabolism and Decreased Responsiveness May Be Related

Julie Kanter, MD1, Dk McLaughlin2*, J Dimitry1*, S. Rogers, PhD3*, Pj Kell1*, WA Frazier, PhD4* and A. Doctor, MD3*

1Pediatric Hematology/Oncology, Washington University, St. Louis, MO
2Pediatrics, Washington University, St. Louis, MO
3Pediatric, Washington University, St. Louis, MO
4Department of Biochemistry, Washington University, St. Louis, MO

Elevated Procoagulant Activity Due to Phosphatidylserine Exposure on Red Blood Cells during Storage

Jin Zhou1*, Chengfang Lu1*, Hongjuan Yu1*, Jinxiao Hou1*, Shuchuan Liu1*, Ming Ma1*, Gary Gilbert2* and Jialan Shi2

1Department of Medicine, Hematology, The First Hospital Affiliated Harbin Medical University, Harbin, China
2Department of Medicine, Hematology, VA Boston Healthcare System, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

*signifies non-member of ASH