Jana Kotaskova, MSc.^1*, Marek Mraz, MSc.^1*, Boris Tichy, Dr.^1*, Jitka Kabathova, Dr.^1*, Jitka Malcikova, MSc.^1*, Martin Trbusek, PhD.^1*, Hana Francova, MSc.^1*, Michael Doubek, MD, PhD.^2*, Yvona Brychtova, MD^2*, Jiri Mayer, MD, PhD.² and Sarka Pospisilova, PhD.^1*

¹Department of Internal Medicine - Hematooncology, Center of Molecular Biology and Gene Therapy, University Hospital Brno and Medical Faculty MU, Brno, Czech Republic
²Department of Internal Medicine - Hematooncology, University Hospital Brno and Medical Faculty MU, Brno, Czech Republic

Mascha Binder^1*, Fabian Müller^2*, Mareike Frick^2*, Claudia Wehr^2*, Milena Pantic^2*, Dietmar Pfeifer^3*, Renata Pasqualini^4*, Wadih Arap, MD, PhD^4*, Hendrik Veelken, MD², Roland H. Mertelsmann, MD, PhD² and Martin Trepel^1*

¹Hematology/Oncology, University of Hamburg Medical Center, Hamburg, Germany
²Hematology/Oncology, University of Freiburg Medical Center, Freiburg, Germany
³Dept. of Hematology/Oncology, University Medical Center Freiburg, Freiburg, Germany
⁴MD Anderson Cancer Center, Houston, TX

Sami Malek, MD, Sam Fossum^*, Kerby Shedden^* and Peter Ouillette^*

Comprehensive Cancer Ctr., Univ. of Michigan, Ann Arbor, MI

Tait Shanafelt, MD, Neil E. Kay^*, Gregory Jenkins^*, Timothy G. Call^*, Clive S. Zent^*, Diane F. Jelinek^*, Justin Boysen^*, Susan Schwager^*, Deborah Bowen^*, Liam Zakko^*, Susan L. Slager^* and Curtis A. Hanson^*

Mayo Clinic, Rochester, MN

Tait Shanafelt, MD¹, Neil E. Kay^1*, Kari Rabe^1*, Timothy G. Call^1*, Clive S. Zent^1*, Kami Maddocks, MD^2*, Diane F. Jelinek^1*, Justin Boysen^1*, Deborah Bowen^1*, Susan Schwager^1*, Gregory Jenkins^1*, Susan L. Slager, PhD^1* and Curtis A. Hanson^1*

¹Mayo Clinic, Rochester, MN
²Hematology/Oncology, Ohio State University James Cancer Center, Columbus, OH

Maite P. Quiroga, BS^*, Antonina Kurtova, MS^*, William Wierda, MD, PhD, Michael Keating, MB, BS and Jan A. Burger, MD, PhD

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Roxana S Dronca, MD^*, Curtis A. Hanson, MD^*, Dragan Jevremovic, MD, PhD^*, C. Scott Collins, MD^*, Kari Rabe, MS^*, Jessica Sonbert^*, Susan L. Slager, PhD^*, Susan Schwager^*, Tait D. Shanafelt, MD^*, Neil E. Kay, MD^* and Clive S. Zent, MD^*

Division of Hematology, Mayo Clinic, Rochester, MN

Céline Pebrel-Richard, PhD^1*, Richard Veyrat Masson, MD, PhD^1*, Frédérique Dubois-Galopin, PhD^1*, Jean-Jacques Guérin^1*, Laurent Guillouard^1*, Jacques Chassagne, PhD^1*, Jacques-Olivier Bay, MD, PhD², Olivier Tournilhac, MD, PhD^2*, Karin Tarte, PhD^3* and Marc G Berger, MD, PhD¹

¹Hematology (Biology), EA 3846, CHU, Clermont-Ferrand, France
²Service de Thérapie Cellulaire et d'Hématologie Clinique Adulte, EA 3846, Hotel-Dieu, Clermont-Ferrand, France
³Inserm U917-MICA, Faculté de Médecine de Rennes, Rennes, France

Francesco Bertoni, MD¹, Marta Scandurra^1*, Michaela Cerri^2*, Clara Deambrogi, PhD^3*, Paola MV Rancoita^1*, Silvia Rasi^3*, Francesco Forconi^4*, Maurilio Ponzoni^5*, Santiago Montes-Moreno^6*, Miguel A. Piris^6*, Giorgio Inghirami^7*, Andrea Rinaldi^1*, Emanuele Zucca^1*, Ivo Kwee^1*, Gianluca Gaidano^2* and Davide Rossi^2*

¹Laboratory of Experimental Oncology and Lymphoma Unit, Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland
²Division of Hematology, Department of Clinical and Experimental Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
³Dept. of Med. Sciences & IRCAD, Amedeo Avorgadro Univ., Novara, Italy
⁴Ematologia e Trapianti, Università di Siena - AOUS, Siena, Italy
⁵HSR, Milan, Italy
⁶CNIO, Madrid, Spain
⁷Univ. of Turin, Turin, Italy

Daphne Friedman, MD¹, J. Brice Weinberg, MD², Karen M Bond^2*, Alicia D Volkheimer^2*, Youwei Chen^2* and Joseph R Nevins, PhD^3*

¹Medical Oncology, Duke University Medical Center, Durham, NC
²VA & Duke Medical Centers, Durham, NC
³Inst. Genome Sciences and Policy, Duke University, Durham, NC

Holger Nückel, MD^1*, Ulrich H Frey, MD^2*, Ludger Sellmann, MD^1*, Crista H Collins^3*, Ulrich Duehrsen, MD⁴ and Winfried Siffert, MD^5*

¹Department of Haematology, University Hospital of Essen, Essen, Germany
²Department of Anaesthesia and Intensive care, University Hospital of Essen, Essen, Germany
³Institute of Pahrmacogenetics, University Hospital Essen, Essen, Germany
⁴Department of Hematology, University Hospital Essen, Essen, Germany
⁵Institute of Pharmacogenetics, University Hospital of Essen, Essen, Germany

Christian P Pallasch, MD^1*, Alexandra Schulz^1*, Nadine Kutsch^1*, Janine Schwamb^1*, Susanne Hagist, MD^1*, Claudia Wickenhauser, MD^2*, Alfred Ultsch, PhD^3*, Hamid Kashkar, PhD^4*, Michael Hallek, MD¹ and Clemens-Martin Wendtner, MD¹

¹Department I of Internal Medicine, Center of Integrated Oncology Cologne Bonn, University of Cologne, Cologne, Germany
²Department of Pathology, University of Cologne, Cologne, Germany
³Databionics Research Group, Department of Mathematics and Computer Science, Philipps-University Marburg, Marburg, Germany
⁴Institute for Medical Microbiology and Immunology, University of Cologne, Cologne, Germany

Eva Rossmann, MD, PhD^1*, Parviz Kokhaei, PhD^1*, Fariba Mozaffari, PhD^1*, Marzia Palma, MD^1*, Anders Osterborg, MD, PhD², Hakan Mellstedt, Prof, MD, PhD^1* and A. Raja Choudhury, MSc, PhD^3*

¹Departments of Hematology and Oncology, Karolinska University Hospital Solna, Stockholm, Sweden
²Deptartment of Hematology, Karolinska Hospital, Stockholm, Sweden
³Oncology Pathology, R8:01, Stockholm, Sweden

Christian P Pallasch, MD^1*, Susanne Ulbrich, MD^1*, Reinhild Brinker^1*, Robert A Uger, PhD^2*, Michael Hallek, MD¹ and Clemens-Martin Wendtner, MD¹

¹Department I of Internal Medicine, Center of Integrated Oncology Cologne Bonn, University of Cologne, Cologne, Germany
²Trillium Therapeutics Inc., Toronto, ON, Canada

José-Ángel Hernández^1*, Ana-Eugenia Rodríguez^2*, Marcos González^3*, Rocío Benito^2*, Celia Fontanillo^2*, Virgilio Sandoval^4*, Mercedes Romero^5*, Guillermo Martín-Núñez^6*, Alfonso García de Coca^7*, Rosa Fisac^8*, Josefina Galende^9*, Isabel Recio^10*, Francisco Ortuño^11*, Juan-Luis García^2*, Javier de las Rivas^2*, Norma-Carmen Gutiérrez^3*, Jesús-Maria Hernández^3* and J.F. San Miguel³

¹Hematología, Hospital Infanta Leonor, Madrid, Spain
²IBMCC, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC, Salamanca, Spain
³Hematología, IBMCC, Centro de Investigación del Cáncer, Universidad de Salamanca-CSIC; Hospital Clínico Universitario, Salamanca, Spain
⁴Hematología, Hospital Virgen Blanca, León, Spain
⁵Hematología, Hospital del Río Hortega, Valladolid, Spain
⁶Hematología, Hospital Virgen del Puerto, Plasencia (Cáceres), Spain
⁷Hospital Clínico Universitario de Valladolid, Valladolid
⁸Hematología, Hospital General, Segovia, Spain
⁹Hematología, Hospital del Bierzo, Ponferrada (León), Spain
¹⁰Hematología, Hospital Nuestra Señora de Sonsoles, Avila, Spain
¹¹Hematología, Hospital Morales Meseguer, Murcia, Spain

Sami Malek, MD and Peter Ouillette^*

Comprehensive Cancer Ctr., Univ. of Michigan, Ann Arbor, MI

Christian P Pallasch, MD^*, Susanne Hagist, MD^*, Michaela Patz^*, Alexandra Schulz^*, Svenja Debey^*, Daniela Eggle^*, Joachim L Schultze, MD^*, Michael Hallek, MD and Clemens-Martin Wendtner, MD

Department I of Internal Medicine, Center of Integrated Oncology Cologne Bonn, University of Cologne, Cologne, Germany

Andy C Rawstron, BSc, PhD¹, Darren J Newton^2*, Ruth M. de Tute^1*, Jane Shingles^2*, Fiona L Bennett^3*, Paul A.S. Evans^3*, Sheila J.M. O'Connor^3*, Andrew S Jack³ and Peter Hillmen³

¹H.M.D.S., Leeds Teaching Hospitals, Leeds, United Kingdom
²Experimental Haematology, Leeds Institute for Molecular Medicine, Leeds, United Kingdom
³Hmds, Leeds Teaching Hospitals, Leeds, United Kingdom

Thorsten Zenz^1*, Jana Smadova^2*, Dominik Vollmer^1*, Martin Trbusek^2*, Axel Benner^3*, Sonja Häbe^1*, Tina Denzel^1*, Jitka Malcikova^4*, Sim Truong^5*, Nancy Patten^5*, David Oscier^6*, Rachel Ibbotson^6*, Anne Gardiner^6*, Ian Tracy^6*, Ke Lin^7*, Andrew Pettitt^7*, Sarka Popsilova^2*, Jiri Mayer⁸, Hartmut Döhner¹ and Stephan Stilgenbauer¹

¹University of Ulm, Ulm, Germany
²University of Brno, Brno, Czech Republic
³Biostatistics, DKFZ, Heidelberg, Germany
⁴Hematooncology, Center of Molecular Biology and Gene Therapy, University Hospital Brno and Medical Faculty MU, Brno, Czech Republic
⁵Roche Molecular Systems, Pleasanton, CA
⁶Department of Haematology, Royal Bournemouth Hospital, Bournemouth, United Kingdom
⁷University of Liverpool, Liverpool, United Kingdom
⁸Hematology/Oncology, Masaryk University Hospital, Brno, Czech Republic

Jerry D Henderson, MD^1*, Susan M O'Brien, MD², Xuemei Wang, MS^3*, Stefan H Faderl, MD^2*, Alessandra Ferrajoli, MD², Guillermo Garcia-Manero, MD^2*, Constantine S. Tam, MB.BS⁴, Jan A Burger, MD, PhD², Lynne V Abruzzo, MD, PhD⁵, Ellen Schlette, MD⁵, Susan Lerner^2*, Michael J Keating, MBBS² and William G Wierda, MD, PhD²

¹General Internal Medicine, U.T.M.D. Anderson Cancer Center, Houston, TX
²Leukemia, U.T.M.D. Anderson Cancer Center, Houston, TX
³Quantitative Sciences Division, U.T.M.D. Anderson Cancer Center, Houston, TX
⁴Haematology, St Vincent's Hospital, Fitzroy, Australia
⁵Hematopathology, U.T.M.D. Anderson Cancer Center, Houston, TX

H. Elizabeth Broome, MD¹, Laura Rassenti, PhD², Jack D. Bui, MD, PhD^1*, Lilly Meyer^1* and Thomas J. Kipps, MD, PhD²

¹Pathology, Moores UCSD Cancer Center, La Jolla, CA
²Moores Cancer Ctr., Univ. of California, San Diego, La Jolla, CA

Mirza Suljagic, DVM, PhD^1*, Luca Laurenti, MD^2*, Muhammad Alam, MD^3*, Pablo G Longo, MD¹, Sami N Malek, MD³ and Dimitar G Efremov, MD, PhD¹

¹Molecular Hematology, ICGEB, Rome, Italy
²Istituto di Ematologia, Catholic University Hospital A. Gemelli, Rome, Italy
³Comprehensive Cancer Ctr., Univ. of Michigan, Ann Arbor, MI

Martin Klabusay, MD, PhD^1*, Viera Kuhrova^2*, Viera Hrabcakova^2*, Petr Coupek^3* and Jiri Mayer⁴

¹Internal Medicine - Hematooncology, Masaryk University, Brno, Czech Republic
²Internal Medicine - Hematooncology, University Hospital Brno, Brno, Czech Republic
³Czech Geological Survey, Brno, Czech Republic
⁴Hematology/Oncology, Masaryk University Hospital, Brno, Czech Republic

Karen S Rees-Unwin, PhD^1*, Robin Faragher, PhD^1*, Claire V Hutchinson, FRCPath^1*, Richard D Unwin, PhD^2*, Julie Adams, PhD^3*, Andrew Pettitt, PhD, FRCPath^4*, Alison H Banham, PhD^5*, Karen Pulford, PhD⁵ and John Burthem, PhD, FRCPath^6*

¹Cancer Studies and Imaging Sciences, University of Manchester, Manchester, United Kingdom
²Cancer Studies and Imaging Sciences, Stem Cell and Leukaemia Proteomics Laboratory, Manchester
³Clinical Haematology, Manchester Royal Infirmary, Manchester
⁴University of Liverpool, Liverpool, United Kingdom
⁵Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom
⁶Clinical Haematology, Manchester Royal Infirmary, Manchester, United Kingdom

Philip T Murphy, MD^1*, Brendan p Power, PhD^2*, Patrick D Thornton, MD^1* and Judith H Harmey, PhD^2*

¹Hematology, Beaumont Hospital, Dublin, Ireland
²Molecular and Cellular Therapeutics, Royal College of Surgeons, Dublin 2, Ireland

Anna Guarini^1*, Marilisa Marinelli^1*, Simona Tavolaro^1*, Isabella Torrente^2*, Emanuele Bellacchio^2*, Monia Magliozzi^2*, Simona Santangelo^1*, Nadia Peragine^1*, Maria Stefania De Propris^1*, Mauro Nanni^1*, Sabina Chiaretti^1*, Francesca Romana Mauro^1*, Ilaria Del Giudice^1*, Bruno Dallapiccola^2* and Robert Foa^1*

¹Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy
²Genetics, CSS Mendel, Rome, Italy

Nina C Dempsey^1*, Francesca Leoni^1*, John H.H. Williams^1* and Christine Hoyle²

¹Department of Biological Science, Chester Centre for Stress Research, Chester, England
²Glan Clwyd Hospital, Rhyl, United Kingdom

Ellen Schlette, MD¹, Constantine S. Tam, MB.BS², Marco Herling, MD^3*, Carlos Bueso-Ramos, MD, PhD^1*, William Wierda, MD^4*, Alessandra Ferrajoli, MD^4*, Susan O'Brien, MD^4*, Michael Keating, MB.BS^4* and Dan Jones^1*

¹Department of Hematopathology, M.D. Anderson Cancer Ctr., Houston, TX
²Haematology, St Vincent's Hospital, Fitzroy, Australia
³Cologne University, Cologne, Germany
⁴Department of Leukemia, M.D. Anderson Cancer Ctr., Houston, TX

Vamsidhar Velcheti, MD^1*, Srikanth Tamma, MD^1*, Zoe L Larned, MD^1*, Jyotsna Fuloria, MD¹, Li Li, MD, PhD¹, Francis R Rodwig, MD^1*, John T. Cole, MD¹, Felipe Samaniego, MD^2* and Om Prakash, PhD^1*

¹Ochsner Clinic Foundation, New Orleans, LA
²MD Anderson Cancer Center, Houston, TX

Samir G Agrawal, MD, PhD^1*, Feng-Ting Liu, MB, PhD^2*, Jerome Giustiniani, PhD^3*, Li Jia, MB, PhD^4*, John G. Gribben, MD, DSc⁵ and Armand Bensussan, PhD^3*

¹Centre for Haematology, Institute of Cell and Molecular Science, Queen Mary University of London, London, United Kingdom
²Haematology, ICMS, London, United Kingdom
³INSERM U841, France
⁴Haematology, ICMS, Queen Mary University of London, London
⁵Institute of Cancer, Centre for Medical Oncology, Barts and the London School of Medicine, London, United Kingdom