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901.O2.8 Supportive Care and Methods

Monday, December 8, 2008: 3:30 PM-5:30 PM
3007-3009-3011 - West (Moscone Center)
Moderators:
Saro Armenian, DO, MPH and Lillian Sung, MD
3:30 PM
Comparison of Infection-Related Hospitalization Risk and Associated Costs among Patients Receiving Sargramostim (Leukine®), Filgrastim (Neupogen®), and Pegfilgrastim (Neulasta®) for Chemotherapy-Induced Neutropenia

Edmond L Toy, PhD1*, Francis Vekeman, MA2*, François Laliberté, MA2*, Bree Dority, PhD1*, Daniel Perlman1*, Victoria Barghout, MSPH3*, Mei Sheng Duh, MPH, ScD4* and Mark Lawrence Heaney, MD, PhD5

1Analysis Group, Inc., Lakewood, CO
2Groupe d'Analyse, Ltée, Montréal, QC, Canada
3Bayer HealthCare Pharmaceuticals Inc., Wayne, NJ
4Analysis Group, Inc., Boston, MA
5Memorial Sloan-Kettering Cancer Ctr., New York, NY

3:45 PM
Serum Lactic Acid (LA) as a Predictor of Septic Shock in Patients with Hematologic Malignancies (HM) Who Develop Febrile Neutropenia

Anthony R Mato, MD1*, Selina Luger, MD2, Alison W. Loren, MD1*, Daniel F Heitjan, PhD1*, Erin R. Olson, MD1*, Chaitra S Ujjani, MD1*, Samantha Jacobs, MD1*, Payal D. Shah, BS1*, Andrea N. Miltiades, BS1*, David Wang, MS1*, Kevin Lux, MS1*, Elise Chong, BS1*, Laura L Belby, BS3*, Donald E. Tsai, MD1* and Barry D. Fuchs, MD4*

1Hematology and Oncology, University of Pennsylvania, Philadelphia, PA
2Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
3University of Pennsylvania, Philadelphia, PA
4Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA

4:00 PM
Deficiency of Mannose-Binding Lectin Is a Risk Factor for Invasive Pulmonary Aspergillosis in Patients with Multiple Myeloma: An Analysis of 482 Patients

Elias J. Anaissie, MD1, Wei-zhi Zhao2*, Yue-Jin Wen2*, Monica Grazziutti2*, Wen Ling2*, Jeanette Lee2*, Frits van Rhee2* and Bart Barlogie2*

1Univ. of Arkansas for Med. Sciences, Little Rock, AR
2Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR

4:15 PM
Development of the Anemia Impact Measure (AIM): A Disease-Specific Patient Reported Outcome (PRO) Instrument to Measure Anemia Symptoms and Their Impact on Functioning in Cancer Patients Receiving Chemotherapy

Leah Kleinman, DrPH1*, Katy Benjamin, PhD2*, Hema Viswanathan, PhD3*, Maria Stoeckl Mattera, MPH2*, Linda D. Bosserman, MD, FACP4*, Douglas W. Blayney, MD5 and Dennis Revicki, PhD2*

1United BioSource Corporation, Seattle, WA
2United BioSource Corporation, Bethesda, MD
3Amgen Inc., Thousand Oaks, CA
4Wilshire Oncology Medical Group, Inc., La Verne, CA
5University of Michigan Cancer Center, Ann Arbor, MI

4:30 PM
Patients Are Willing to Trade off Efficacy, Safety, and Administration Attributes of Chronic Idiopathic Purpura (ITP) Therapy: Results from a Large North American Discrete Choice Study

Kelly M Grotzinger1*, F. Reed Johnson2*, A. Brett Hauber2*, Semra Özdemir3* and Mohan V Bala1*

1GlaxoSmithKline, Collegeville, PA
2RTI Health Solutions, Research Triangle Park, NC
3University of North Carolina - Chapel Hill, Chapel Hill, NC

4:45 PM
Choosing First-Line Therapy for Follicular Lymphoma (FL): A Decision Analysis

Rebecca L. Olin, MD1, Peter A. Kanetsky, PhD, MPH2*, Thomas Ten Have, PhD, MPH2*, Sunita Dwivedy Nasta, MD1, Stephen J. Schuster, MD1 and Charalambos Andreadis, MD, MSCE3

1Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA
2Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA
3Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA

5:00 PM
Expectation Bias-the Main Culprit for Large Number of Inconclusive Randomized Controlled Trials in Hematological Malignancies

Anja Magazin1*, Ambuj Kumar, MD, MPH1*, Heloisa Soares2*, Michael Schell3*, Iztok Hozo, Professor, of, Mathematics, Ph.D4* and Benjamin Djulbegovic, MD, PhD5

1Moffitt Cancer Center, Tampa, FL
2Mount Sinai Medical Center, Miami, FL
3Biostatistics Core, H. Lee Moffitt Cancer Center, Tampa, FL
4Department of Mathematics and Actuarial Science, Indiana University, Gary, IN
5H. Lee Moffitt Cancer Center, Tampa, FL

5:15 PM
Evaluation of Conflicts of Interest in Basic Science Studies Evaluating Erythropoietin and Erythropoietin Effects of Solid Cancer Cell Lines

Sara E Barnato, MD1*, Simone N Boyle, BA2*, Adam Kuykendal, MD3*, Stephen Y Lai, MD, PhD4*, Robin L Wagner2*, Carolyn E Goldstein5*, Athena T Samaras, BA2*, Dennis P West, PhD6*, Jacob Tallman5*, Michael Henke, MD7*, A. Oliver Sartor, MD8* and Charles L. Bennett, MD, PhD, MPP9

1McGaw Medical Center, Northwestern University, Chicago, IL
2Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL
3Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
4Otolaryngology, University of Pittsburgh Medical Center and University of Pittsburgh Cancer Institute, Pittsburgh, PA
5Hematology/Oncology, Northwestern Feinberg School of Medicine, Chicago, IL
6Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL
7Radiation Oncology, Radiological University Clinic, Freiburg, Germany
8Hematology/Oncology, Tulane Medical School and Cancer Center, New Orleans, LA
9Hematology/Oncology, Northwestern University, Chicago, IL

*signifies non-member of ASH