Before you can access ASH's online program, you must agree to the following:
Last updated January 16, 2009. Please note that this site represents the latest program changes
and differs from the print version in some details.

733.O2.8 Autologous Transplantation: Lymphoma

Tuesday, December 9, 2008: 7:00 AM-9:00 AM
Yerba Buena Ballroom Salon 7 (San Francisco Marriott)
Moderators:
Christian Gisselbrecht and Charalambos Andreadis, MD, MSCE
7:00 AM
Early Consolidation with Myeloablative Radiochemotherapy Followed by Autologous Stem Cell Transplantation in First Remission in Mantle Cell Lymphoma: Long Term Follow up of a Randomized Trial of the

Martin H. Dreyling, MD1, Eva Hoster, PhD2*, Achiel Van Hoof3, Bernd Metzner4, Christian Gisselbrecht5, Michael Pfreundschuh, MD, PhD6, Marcel Reiser7*, Lorenz H. Truemper, MD, PhD8, Hjalmar Steinhauer9*, Jean-Michel Boiron, MD, PhD10, Marc Boogaerts, MD, PhD11, Vittorio Silingardi12*, J.C. Kluin-Nelemans, MD, PhD13, Michael Unterhalt14* and Wolfgang Hiddemann15

1Medizinische Klinik III, Klinikum der Universitaet Muenchen-Grosshadern, Munich, Germany
2Medizinische Klinik III, Klinikum der Universitat Muenchen - Grosshadern, Munich, Germany
3A. Z. Sint Jan AV, Brugge, Belgium
4Klinikum Oldenburg, Oldenburg, Germany
5Dept. of Hematology, St. Louis Hospital, Paris, France
6Klinik f. Innere Medizin I, Homburg, Saar, Germany
7Klinikum, Universität zu Köln, Köln, Germany
8Dept. of Hem. and Onc., Georg August University, Gottingen, Germany
9Carl-Thiem-Klinikum, Cottbus, Germany
10EFS-AL, Bordeaux, Cedex, France
11Hematology, U.Z. Gasthuisberg, Leuven, Belgium
12Dept. of Medical Oncology, University of Modena, Modena, Italy
13Hematology, University Medical Centre Groningen, Groningen, Netherlands
14Medizinische Klinik III, Klinikum der Universitaet Muenchen - Grosshadern, Munich, Germany
15III. Dept. of Internal Medicine, University of Munich, Munich, Germany

7:15 AM
High-Dose Chemotherapy Followed by Autologous Stem Cell Transplantation (auto-SCT) Versus CHOP Regimen in Patients with Untreated Aggressive Non-Hodgkin’s Lymphoma: An Update of the GOELAMS 072 Trial with a Median Follow-up of 9.8 Years

Thomas Gastinne1*, Gandhi Damaj2*, Thierry Lamy, PhD3*, Norbert Ifrah4*, Eric Deconinck5, Remy Gressin, MD6, Philippe Colombat, MD, PhD7, Vincent Delwail8*, Christian Berthou9*, Jean François Rossi10*, Jean Luc Harousseau11* and Noel-Jean Milpied, PhD12

1CHU de Nantes, Nantes, France
2Groupe Francophone des Myelodysplasies (GFM), Bobigny, France
3Haematology, CHU Rennes, Rennes, France
4service Hématologie, CHU Angers,, Angers, France
5Hematology, INSERM UMR645 - CHU Jean Minjoz, Besançon
6Dept. of Onc.-Haem., CHU Michallon, Grenoble, France
7Service d'Hématologie et Thérapie Cellulaire, CHU de Tours, Tours, France
8Hématologie et Oncologie médicale, CHU Poitiers, Poitiers, France
9CHU Brest, Brest, France
10INSERM U847, Montpellier, France
11Service d'Hématologie, CHU Hotel Dieu, Nantes, France, NAntes, France
12Hopital Haut Leveque - Pessac, Pessac, France

7:30 AM
Survival Impact of Rituximab Combined to ACVBP (R-ACVBP) in 209 Poor Risk Diffuse Large B-Cell Lymphoma (DLBCL) Patients Treated with Upfront High-Dose Consolidative Autotransplantation (HDC) : A GELA Phase II Study

Christian Gisselbrecht1, Olivier Fitoussi2*, Karim Belhadj3*, Nicolas Mounier, MD4*, Pierre Feugier, MD5*, Bertrand Coiffier6, Christian Recher, M.D;, Ph.D7*, Olivier Casasnovas, MD8*, Catherine Sebban, MD9*, Christophe Ferme, MD10*, Josette Briere11*, Herve Tilly, MD12 and Corinne Haioun13

1Dept. of Hematology, St. Louis Hospital, Paris, France
2Oncologie, Polyclinique Bordeaux Nord, Bordeaux, France
3Service D'hématologie Clinique, Henri Mondor, Créteil, France
4CHU Nice, Nice, France
5CHU de Nancy - Hopital Brabois, Vandoeuvre les Nancy, France
6Centre Hospitalier Lyon-Sud, Pierre-Benite
7Service d'Hematologie, CHU Toulouse, Toulouse, France
8CHU Dijon, Dijon, France
9Hematology, centre Léon Bérard, Lyon, France
10Dept. of Medicine, Institut Gustave Roussy, Villejuif, France
11Service d'onco-hématologie, Hôpital Saint-Louis APHP, INSERM U728 - Institut Universitaire d'Hématologie, Paris, France
12Centre Henri Becquerel, Rouen, France
13Service d'Hématologie Clinique, Hôpital Henri Mondor, Créteil, France

7:45 AM
Autologous Stem Cell Transplantation after Myeloablative Therapy in First Remission May Be Beneficial in Patients with Advanced Stage Follicular Lymphoma after Front-Line Therapy with R-CHOP. An Analysis of Two Consecutive Studies of the German Low Grade Lymphoma Study Group (GLSG) 

Wolfgang Hiddemann1, Christian Buske, Dr2*, Michael Kneba, MD, PhD3, Martin Dreyling4, Norbert Schmitz5*, Eva Lengfelder6*, Rudolf Schmits7*, Marcel Reiser8*, Bernd Metzner9 and Michael Unterhalt, PhD10*

1Third Department of Internal Medicine, University of Munic, Munich, Germany
2CCG Leukemia, Helmholtz Zentrum muenchen, Munich, Germany
32nd Dept. of Internal Medicine, Univ. Schleswig-Holstein,, Kiel, Germany
4Department of Internal Medicine III, University Hospital of Munich, Großhadern, Munich, Germany
5Depatment of Hematology & Stem cell transplantation, Asclepios Clinic St. Georg, Hamburg, Germany
6Dept. of Hematology/Oncology, University of Heidelberg, Mannheim, Germany
7Hämatologie / Onkologie, Universitätsklinik Homburg, Homburg / Saar, Germany
8DSHNHL, Homburg, Saar, Germany
9Klinikum Oldenburg, Oldenburg, Germany
10Department of Internal Medicine III, University of Munich-Hospital Großhadern, Munich, Germany

8:00 AM
Autologous Stem Cell Transplantation (auto-SCT) as the Treatment of Choice for Follicular Lymphoma Patients in First Relapse: Final Analysis of the Outcome of  175 Patients Treated in the GELA/GOELAMS FL 2000 Study

Steven Le Gouill, MD, PhD1*, Sophie De Guibert2*, Christelle Volteau3*, Marion Fournier4*, Franck Morschhauser5*, Chantal Doyen6, Pauline Brice7, Corinne Haioun8*, Charles Foussard9* and Gilles Andre Salles, MD, PhD10

1Haematology, CHU Nantes, Nantes, France
2Hematology department, CHu de Rennes, Rennes, France
3Promotion de la recherche et statistiques, CHU de Nantes, Nantes, France
4Biostatistic department, Gelarc, Lyon, France
5Hematology, Centre Hospitalier Universitaire, Lille, France
6Hematology department, Université Catholique de Louvain, Louvain, Belgium
7Hopital Saint Louis
8Hopital Henri Mondor, Creteil, France
9Hematology, CHU d'Angers, Angers, France
10Hematologie, Centre Hospitalier Lyon-Sud, Pierre-Benite, France

8:15 AM
Patients with Mature T-Cell Lymphoma Show High Relapse Rates after High Dose Therapy and Autologous Stem Cell Transplantation

Maike Nickelsen, MD1*, Carmen Canals Sr., MD2*, Norbert Schmitz, MD, PhD1, Charalampia Kyriakou, MD, PhD3, Monika Engelhardt, MD, PhD4, Thomas Relander, MD5*, Werner Linkesch, MD, PhD6*, Vladimir Koza, MD7*, Giovanna Meloni, MD8*, Armando Lopez-Guillermo, MD9, Karel Indrac, MD10*, Dolores Caballero, MD11*, Hannes Wandt, MD, PhD12*, Niklas Theorin, MD13*, Bertram Glass, MD, PhD1* and Anna Sureda, Md, PhD14*

1Hematology and Stem Cell Transplantation, ASKLEPIOS Klinik St. Georg, Hamburg, Germany
2Lymphoma Working Party, EBMT, Barcelona, Spain
3Haematology, Nort West London NHS Trust, NPH Hospital, London, United Kingdom
4University Hospital, Freiburg, Germany
5Hematology, University Hospital, Lund, Sweden
6Med. Univ. Graz, Graz, Austria
7Dept. of Hematology and Oncology, University Hospital Pilsen, Pilsen, Czech Republic
8Division of Hematology, Department of Cellular Biotechnologies and Hematology, “Sapienza” University, Rome, Italy
9Hematology, Hospital Clinic, Barcelona, Spain
10Haemato-Oncology, University Hospital, Olomouc, Czech Republic
11Hematology-BMT Unit, Hospital Clínico Salamanca
12Medical Department 5, Klinikum Nuernberg Nord, Nuernberg, Germany
13Dept. of Hematology, University Hospital, Linköping, Sweden
14Clinical Hematology Division, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

8:30 AM
Pre-Transplant Evaluation with Both CT and PET Following Second-Line Therapy Is Essential for Predicting Outcome in Patients with Transplant-Eligible Relapsed and Primary Refractory Hodgkin Lymphoma

Alison J. Moskowitz, MD1, Stephen D. Nimer2, Andrew D. Zelenetz, MD, PhD3*, Tarun Kewalramani, MD4*, Jill M Vanak, ACNP5*, Jocelyn c Maragulia5*, Joachim Yahalom, MD6 and Craig Moskowitz, MD7

1Education and Training, Medical Oncology, New York, NY
2Laboratory of Molecular Aspects of Hematopoiesis, Memorial Sloan Kettering Cancer Center, New York, NY
3Memorial Sloan-Kettering Cancer Center, New York, NY
4Lahey Clinic, MA
5Medicine, MSKCC, NY, NY
6Memorial Sloan-Kettering Cancer Ctr., New York, NY
7Memorial Sloan Kettering Cancer Ctr., New York, NY

8:45 AM
Normalization of FDG-PET Pre-ASCT with Additional Non-Cross Resistant Chemotherapy Improves EFS in Patients with Relapsed and Primary Refractory Hodgkin Lymphoma-Memorial Sloan Kettering Protocol 04-047Clinically Relevant Abstract

Craig H. Moskowitz, MD1, Stephen D. Nimer2, Andrew D. Zelenetz, MD, PhD3*, Paul A. Hamlin Jr., MD3, Steven M. Horwitz, MD3, Ariela Noy, MD4, Carol S. Portlock, MD4, David J. Straus, MD5, John Gerecitano, MD, PhD6, Tarun Kewalramani, MD7*, Jill M. Vanak, ACNP8*, Jocelyn C. Maragulia8* and Joachim Yahalom, MD4

1Memorial Sloan Kettering Cancer Ctr., New York, NY
2Laboratory of Molecular Aspects of Hematopoiesis, Memorial Sloan Kettering Cancer Center, New York, NY
3Memorial Sloan-Kettering Cancer Center, New York, NY
4Memorial Sloan-Kettering Cancer Ctr., New York, NY
5Medicine, MSKCC, New York, NY
6Memorial Sloan-Kettering Cancer Ctr., Lymphoma Service, New York, NY
7Lahey Clinic, MA
8Medicine, MSKCC, NY, NY

*signifies non-member of ASH