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731.O2.6 Clinical Results - Allogeneic Matched Related Donor Transplantation II

Monday, December 8, 2008: 1:30 PM-3:00 PM
303-305-307 - South (Moscone Center)
Moderators:
Theresa Hahn, PhD and David A. Rizzieri, MD
1:30 PM
Identification of Prognostic Factors Predicting the Outcome of Reduced Intensity Allogeneic Stem Cell Transplantation in Mantle Cell Lymphoma. An Analysis from the Lymphoma Working Party of the EBMT

Stephen P Robinson1*, Anna Sureda2*, Carmen Canals Sr.3*, Jean-Paul Vernant4*, Noel-Jean Milpied, PhD5, Jürgen Finke6, Johan Maertens7*, Jean-Pierre Jouet, MD8, Charles F. Craddock, BM, MRCP, MRCPath9, Karl S Peggs, MD10*, Steven Le Gouill, MD11* and Norbert Schmitz, MD, PhD12

1BMT Unit, University Hospital Bristol, Bristol, United Kingdom
2Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
3Lymphoma Working Party, EBMT, Barcelona, Spain
4Service d'Hématologie Clinique, Hôpital Pitié-Salpêtrière, Paris, France
5Hopital Haut Leveque - Pessac, Pessac, France
6Hematology/Oncology, University Medical Center Freiburg, Freiburg, Germany
7Clinical Hematology Division, Hospital de Sant Pau, Barcelona, Spain
8Maladies du Sang, Rue Michel Polonovski, Lille, France
9Center for Clinical Hematology, Birmingham, ARRAY(0xc83fd08)
10Haematology, University College London, London, United Kingdom
11Haematology, CHU Nantes, Nantes, France
12Hematology and Stem Cell Transplantation, ASKLEPIOS Klinik St. Georg, Hamburg, Germany

1:45 PM
Reduced Intensity Allogeneic Stem Cell Transplantation for Follicular Lymphoma Results in An Improved Progression Free Survival When Compared to Autologous Stem Cell Transplantation. An Analysis from the Lymphoma Working Party of the EBMT

Stephen P Robinson1*, Carmen Canals2*, Didier Blaise, MD3, Kirsty Thomson4*, Robert Foa5, Arturo Iriondo Atienza6*, Jean-Luc Harousseau7, Catherine Cordonnier, MD8, Gordon Cook, MD, PhD9*, Jean-Pierre Jouet, MD10, Jean-Yves Cahn, MD, PhD11, Charles Crawley12, Michel Attal, MD13, Marek Trneny, Assoc., Prof., MD, PhD14, H. Tilly15* and Anna Sureda, MD16*

1BMT Unit, University Hospital Bristol, Bristol, United Kingdom
2Lymphoma Working Party, EBMT, Barcelona, Spain
3Institut Paoli Calmettes, Marseille, France
4Dept. Haematology, University College London, Hertfordshire, United Kingdom
5Dept. of Cellular Biotechnologies & Hematology, University 'Sapienza', Rome, Italy
6Hospital U. Marques de Valdecilla, Santander, Spain
7Hôpital Hôtel Dieu, Nantes, France
8Hematologie Clinique, Hopital Henri Mondor, Creteil, France
9BMT Office, St. James' University Hospital, Leeds, ARRAY(0xc0f75c4)
10Maladies du Sang, Rue Michel Polonovski, Lille, France
11Hematology Department, CHU de Grenoble, Grenoble, France
12Clinical Hematology Division, Hospital Sant Pau, Barcelona, Spain
13Hopital Purpan, Toulouse, France
14First Dept. of Medicine, Charles Univ. General Hosp., Prague, Czech Republic
15Centre Henri Becquerel, Rouen, France
16Hematology, Hospital Sant Pau, Barcelona

2:00 PM
Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (NMHCT) for Patients Relapsing after Autologous Stem Cell Transplantation (autoHCT) for B Cell Non-Hodgkin Lymphoma (NHL)Clinically Relevant Abstract

Cesar O Freytes, MD1, Jeanette Carreras, MPH2*, Mei-Jie Zhang, PhD2*, Ginna G. Laport, MD3, Koen Van Besien, MD4, Hillard M. Lazarus, MD5 and Parameswaran Hari, MD, MS2*

1University of Texas Health Science Center, San Antonio, TX
2Medical College of Wisconsin, Center for International Blood and Marrow Transplant Research, Milwaukee, WI
3Stanford University Medical Center, Stanford, CA
4University of Chicago, Chicago, IL
5University Hospitals Case Medical Center, Cleveland, OH

2:15 PM
RIC Allogeneic Transplantation Improves the Overall and Progression-Free Survival of Hodgkin Lymphoma Patients Relapsing after Autologous Transplantation: A GITMO Retrospective Study Based on Time of HLA-Typing and Donor AvailabilityClinically Relevant Abstract

Barbara Sarina, MD1*, Luca Castagna, MD1*, Fabio Benedetti, MD2*, Francesca Patriarca, MD3*, Michele Malagola, MD4*, Silvia Ferrari, MD5*, Roberto Sorasio, MD6*, Lucia Farina, MD7*, Enrico Morello, MD8*, Alessandro Bonini, MD9*, Nicola Mordini, MD10*, Sergio Tamiazzo, MD11*, Michele Falda, MD12*, Laura Giordano, PhD1* and Paolo Corradini, MD7

1Hematology-Oncology, IRCCS Istituto Clinico Humanitas, Rozzano, Italy
2Hematology, University of Verona, Verona, Italy
3Hematology, University of Udine, Italy
4Chair of Hematology, University of Brescia, Brescia, Italy
5Hematology, Spedali Civili, Brescia
6Hematology, University of Torino
7Hematology - BMT, Istituto Tumori, University of Milano, Milano, Italy
8Hematology, Ospedale Bolzano
9Reggio Emilia Hospital
10Hematology, Ospedale S Croce Cuneo
11Hematology, Ospedale SS Antonio e Biagio, Alessandria, Italy
12Ospedale Maggiore San Giovanni Battista, Torino, Italy

2:30 PM
Donor Versus No Donor Analysis of Newly Diagnosed Myeloma Patients Included in the HOVON 50/54 Study

Henk Lokhorst, MD, PhD1*, Pieter Sonneveld, MD, PhD2*, Bronno van der Holt, PhD3*, Marinus van Oers, MD, PhD4*, Reinier Raymakers, MD, PhD5*, Sonja Zweegman, MD, PhD6, Monique C. Minnema, MD, PhD7 and Mark Zijlmans, MD, PhD3*

1Hematology, University Medical Center Utrecht, Utrecht, Netherlands
2Hematology, Erasmus Medical Center Rotterdam
3Erasmus MC - Daniel den Hoed Cancer Center, Rotterdam, Netherlands
4Amsterdam Medisch Centrum
5University Medical Center Nijmegen
6Dept. of Hematology, 2pk BR018, VUMC, Amsterdam, Netherlands
7Hematology B.02218, UMC Utrecht, Utrecht, Netherlands

2:45 PM
Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation during First Complete Remission Following Imatinib-Combined Chemotherapy in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Shuichi Mizuta1, Masamitsu Yanada2*, Isamu Sugiura3, Fumiharu Yagasaki4*, Toshiaki Yujiri5, Makoto Takeuchi6*, Yoshihiro Hatta7, Yukihiko Kimura8*, Yasunori Ueda, MD9, Heiwa Kanamori10*, Noriko Usui11, Hideki Akiyama12, Yasushi Miyazaki, MD, PhD13, Shigeki Ohtake14, Itsuro Jinnai, MD4, Keitaro Matsuo15*, Tomoki Naoe, MD2 and Ryuzo Ohno, MD16*

1Dept. of Hematology, Fujita Health University, Toyoake, Japan
2Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
3Toyohashi Municipal Hospital, Toyohashi, Japan
4Department of Hematology, Comprehensive Cancer Center, International Medical Center, Saitama Medical University, Saitama, Japan
5Yamaguchi University School of Medicine, Yamaguchi, Japan
6National Hospital Organization Minami-Okayama Medical Center, Okayama, Japan
7Hematology & Rheumatology, Nihon University, Tokyo, Japan
8Tokyo Medical College, Japan
9Kurashiki Central Hospital, Kurashiki, Japan
10Kanagawa Cancer Center, Yokohama, Japan
11Jikei University School of Medicine, Tokyo, Japan
12Hematology Division, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
13Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasakishi, Japan
14Kanazawa University Graduate School of Medical Science, Kanazawa, Japan
15Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
16Japan Adult Leukemia Study Group, Japan

*signifies non-member of ASH