Andreas Hochhaus, MD¹, Martin C Müller, MD^1*, Jerald Radich, MD², Susan Branford³, Benjamin Hanfstein, MD^1*, Philippe Rousselot, MD, PhD^4*, Jeffrey H Lipton, MD, PhD⁵, Eric Bleickardt^6*, Ritwik Sinha^6* and Timothy P Hughes, MD^3*

¹III. Medizinische Klinik, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Germany
²Fred Hutchinson Cancer Rsch. Ctr., Seattle, WA
³Institute of Medical and Veterinary Science, Adelaide, Australia
⁴Hôpital Mignot and CIC9504, Versaille, France
⁵Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
⁶Bristol-Myers Squibb, Wallingford, CT

Roberto Latagliata^1*, Massimo Breccia^1*, Simona Sica^2*, Antonio Spadea, MD, PhD³, Ada D'Addosio^4*, Ida Carmosino^1*, Silvia De Matteis^2*, Caterina Stefanizzi^1*, Paola Volpicelli^1*, Laura Napoleone^1*, Federico Vozella^1*, Maria Concetta Petti^3* and Giuliana Alimena^1*

¹Division of Hematology-Dept. of Cellular Biotechnologies and Hematology, University La Sapienza, Rome, Italy
²Istituto di Ematologia, Catholic University Hospital A. Gemelli, Rome, Italy
³Dept. of Clinical Oncology, Hematology-Istituto Regina Elena, Rome, Italy
⁴Hematology, Hospital Villa S Pietro, Rome, Italy

Weisu Zhang, M.D.^*, Frank Buccini^* and James Weisberger, M.D.^*

BioReference Laboratories, Inc., Elmwood Park, NJ

Jorge Cortes, MD¹, Hagop M Kantarjian², Dong-Wook Kim, MD, PhD³, H. Jean Khoury, MD, FACP⁴, Anna G. Turkina, MD^5*, Zhi-Xiang Shen, MD^6*, Tim H Brummendorf, MD^7*, Mammen Chandy, MD^8*, Steven Arkin, MD⁹ and Carlo Gambacorti-Passerini, MD^10*

¹M.D. Anderson Cancer Center, Houston, TX
²The University of Texas M. D. Anderson Cancer Center, Houston, TX
³Hematology, St. Mary's Hospital, Seoul, South Korea
⁴Emory University, Atlanta, GA
⁵Hematology Research Center, Russia
⁶Rui Jin Hospital, China
⁷Universitäts-Klinikum Hamburg-Eppendorf, Hamburg, Germany
⁸Christian Medical College Hospital, India
⁹Wyeth Research, Cambridge, MA
¹⁰University  Milano Bicocca, Monza, Italy

Carlo Gambacorti-Passerini^1*, Dong-Wook Kim^2*, François-Xavier Mahon^3*, Giuseppe Saglio^4*, Fabrizio Pane⁵, François Guilhot⁶, Michael W.N. Deininger⁷, Arnon Nagler⁸, Alessandro Rambaldi⁹, Enrica Morra^10*, Laura Antolini^1*, IL-Young Kweon^2*, Josy Reiffers^3*, Lucia Tornaghi^1* and Maria Grazia Valsecchi^1*

¹Dept of Clinical and Preventive Medicine, Università Milano Bicocca, Monza, Italy
²Division of Hematology, St. Mary's Hospital, Seoul, South Korea
³Université Victor Ségalen Bordeaux - Institut Bergonié, Bordeaux, France
⁴Internal Medicine and Hematology, Università di Torino - Ospedale San Luigi, Orbassano, Italy
⁵A.F. di Oncologia Ematologica Diagnostica, Azienda Ospedaliera, Napoli, Italy
⁶Clinical Investigational Centre INSERM 802, CHU Poitiers, Poitiers, France
⁷Cell and Developmental Biology, Oregon Health and Science University, Portland, OR
⁸Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Tel Hashomer, Israel
⁹USC Hematology, Ospedali Riuniti di Bergamo, Bergamo, Italy
¹⁰Hematology Department, Ospedale Niguarda Cà Granda, Milan, Italy

Meinolf Suttorp, MD¹, Julia Boehme^1*, Johannes Vaitl^1*, Birgit Mosch^2*, Stefan Pursche^3*, Roland Jung^4*, Ralf Bergmann^2*, Rainer Fischer^5*, Jens Pietzsch^2*, Martin Bornhaeuser^6* and Juerg A. Gasser^7*

¹Schwerpunkt Paediatrische Haematologie/Onkologie, Universitatsklinikum Carl Gustav Carus, Dresden, Germany
²Institute of Radiopharmacy, Forschungszentrum Dresden Rossendorf, Dresden, Germany
³Internal Medicine I, University Hospital, Dresden, Germany
⁴Experimental Center, Medical Faculty Carl Gustav Carus, Dresden
⁵Institute of Pathology, University Hospital, Dresden, Germany
⁶Med. Klinik I, Universitätsklinikum, Dresden, Germany
⁷Musculoskeletal Diseases, Novartis Institutes for Biomedical Research, Basel, Switzerland

Carlo Gambacorti-Passerini^1*, Enrico Maria Pogliani, MD², Michele Baccarani, MD^3*, Giovanni Martinelli^4*, Hagop M Kantarjian⁵, Mammen Chandy^6*, H. Jean Khoury, MD, FACP⁷, Dong-Wook Kim^8*, Tim H Brummendorf^9*, Steven Arkin, MD¹⁰ and Jorge Cortes^11*

¹University  Milano Bicocca, Monza, Italy
²Hematology, New Hospital San Gerardo, Monza, Italy
³Dept. Hematology and Medical Oncology, University of Bologna, Bologna, Italy
⁴Department of Hematology and Oncological Sciences, Seragnoli Institute, University of Bologna, Bologna, Italy
⁵The University of Texas M. D. Anderson Cancer Center, Houston, TX
⁶Christian Medical College Hospital, India
⁷Emory University, Atlanta, GA
⁸Division of Hematology, St. Mary's Hospital, Seoul, South Korea
⁹Hubertus Wald-University Cancer Center, Hamburg-Eppendorf (UCCH), University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany
¹⁰Wyeth Research, Cambridge, MA
¹¹The University of Texas M.D. Anderson Cancer Center, Houston, TX

David M Ross^1*, Andrew Grigg^2*, Anthony Schwarer², Christopher Arthur², Kerryn Loftus^3*, Anthony K Mills^2*, Robin Filshie^2*, Ruth Columbus^2*, John Reynolds^2*, John F Seymour, MB, BS, PhD, FRACP^4*, Susan Branford^1* and Timothy Hughes¹

¹Institute of Medical & Veterinary Science, Adelaide, Australia
²Australasian Leukaemia & Lymphoma Group, Australia
³Novartis Pharmaceuticals, Australia
⁴Dept of Haematology, Peter MacCallum Cancer Institute, Victoria, Australia

Franck Nicolini, MD, PhD¹, Laurence Legros, MD, PhD^2*, Lydia Roy, MD, PhD^3*, Jean-Claude Chomel, MD^4*, Kaddour Chabane, BSc^5*, Sophie Ducastelle, MD^1*, Selim Corm, MD^6*, Mauricette Michallet, MD, PhD⁷, Francois Guilhot, MD³, Ali Turhan, MD, PhD^4* and Sandrine Hayette, PhD^5*

¹Hematology Department, Hospital E. Herriot, Lyon, France
²Hematology department, Hôpital de l'Archet, Nice, France
³CHU de Poitiers, CIC 802 INSERM, Poitiers, France
⁴Laboratory for Hematology and molecular biology, CHU de Poitiers, Poitiers, France
⁵Laboratory for molecular biology and cytogenetics, Centre Hospitalier Lyon Sud, Pierre Benite, France
⁶Hematology department, Hôpital Huriez, Lille, France
⁷Hematology, Hopital Edouard Herriot, Lyon, France

Ruriko Tanaka, MMSc^1*, Matthew S Squires, PhD^2*, Shinya Kimura, MD, PhD^1*, Asumi Yokota, MMSc^1*, Kirsty Mallett, PhD^2*, Tomoko Smyth, PhD^2*, Neil T Thompson, PhD^2*, Rina Nagao^1*, Takahiro Yamauchi, MD³, Takashi Ushiki, MD^4*, John F Lyons, PhD^2* and Taira Maekawa, MD, PhD^1*

¹Department of Transfusion and Cell Therapy, Kyoto University Hospital, Kyoto, Japan
²Astex Therapeutics Ltd., Cambrigde, United Kingdom
³Department of Hematology and Oncology, University of Fukui, Fukui, Japan
⁴Department of Radiation Oncology and Image-Applied Therapy, Kyoto University, Kyoto, Japan

Elias Jabbour^1*, Hagop M. Kantarjian¹, Dan Jones, MD, PhD², Elizabeth Burton^3* and Jorge Cortes¹

¹Leukemia, MD Anderson Cancer Center, Houston, TX
²Hemopathology, UTMD Anderson Cancer Center, Houston, TX
³Leukemia, MD Anderson Cancer Center

Nicola Esposito, PhD^1*, Fabrizio Quarantelli^2*, Luigia Luciano, MD¹, Barbara Izzo, PhD^1*, Anna Lucia Peluso, PhD^1*, Marco Picardi, MD^1*, Susan Branford, PhD³, D.L. White, PhD^3*, Timothy Hughes, PhD³, Jerald Radich^4*, Simona Soverini, PhD^5*, Ilaria Iacobucci, PhD^5*, Giuseppe Saglio, MD^6*, Thea Kalebic, PhD^7*, Mark Thornquist, PhD^8*, Giovanni Martinelli, MD^5* and Fabrizio Pane, MD¹

¹Hematology Unit - CEINGE and Dip. di Biochimica e Biotecnologie Mediche, University of Naples Federico II, Naples, Italy
²Ceinge, University of Naples Federico II, Naples, Italy
³Institute of Medical and Veterinary Science, Adelaide, Australia
⁴Fred Hutchinson Cancer Research Center, Seattle, WA
⁵Department of Hematology/Oncology L. and A. Seràgnoli, University of Bologna, Bologna, Italy
⁶University at Orbassano, Turin, Dept of Cellular Biotechnologies and Hematology, Orbassano, Turin, Italy
⁷Novartis Oncology Clinical Development NJ
⁸Fred Hutchinson Cancer Rsch. Ctr., Seattle, WA

Agnes S. M. Yong, MD, PhD, Keyvan Keyvanfar, BS^*, Rhoda Eniafe, BS^*, Bipin N. Savani, MD, Katayoun Rezvani, MD, PhD^*, Aarthi Shenoy, MD^*, Eleftheria K. Koklanaris, BSN^*, Laura Musse, MSN^*, Theresa Donohue, MS^*, Quan Le, MD, PhD, John M. Goldman, MD^* and A. John Barrett, MD

Hematology Branch, NHLBI/NIH, Bethesda, MD

Richard D. Press, MD, PhD¹, Stephanie G Willis^2*, Jennifer Laudadio^3*, Michael J. Mauro, MD⁴ and Michael W.N. Deininger, MD⁵

¹Prof. & Dir. of Molecular Pathology, Oregon Health & Science Univ., Portland, OR
²Center for Hematologic Malignancies, OHSU Cancer Institute, Portland, OR
³OHSU Pathology
⁴Oregon Health & Science University, Portland, OR
⁵Oregon Health & Science University Cancer Institute, Portland, OR

Deborah L White, PhD^1*, Verity A Saunders^1*, Thea Kalebic, MD^2* and Timothy P Hughes, MD¹

¹Haematology, Institute of Medical and Veterinary Science, Adelaide, Australia
²Novartis Oncology Clinical Development NJ

Dong Hwan Kim, MD, PhD¹, Hee Kyung Ahn, M.D.^1*, Wei Xu, PhD^2*, Suzanne Kamel-Reid, PhD, FACMG³, Xiangdong Liu, Ph.D.^4*, Katherine Siminovitch, M.D./Ph.D.^4* and Jeffrey H. Lipton, MD, PhD⁵

¹Hematology/Med. Oncology, Samsung Medical Center, Seoul, South Korea
²Biostatistics, Princess Margaret Hospital, Toronto, ON, Canada
³Applied Molecular Oncology, Ontario Cancer Institute, Toronto, ON, Canada
⁴Analytical Genetics Technology Centre, Samuel Lunenfield Research Institute, Toronto, ON, Canada
⁵Princess Margaret Hospital, Toronto, ON, Canada

Alexander A. Morley, MD¹, Paul Bartley^1*, David M Ross^2*, Sue Latham^1*, Henry Martin-Harris^1*, Brad Budgen^1*, Vicki Wilczek^1*, Susan Branford^2* and Timothy Hughes²

¹Dept. of Haematology & Genetic Pathology, Flinders Medical Centre, Bedford Park, Australia
²Institute of Medical and Veterinary Science, Adelaide, Australia

Andreas L. Petzer, MD¹, Dominik Wolf, MD^2*, Dominic Fong, MD^2*, Thomas Lion, MD^3*, Irina Dyagil, MD^4*, Zvenyslava Masliak, MD^5*, Darinka Boskovic, MD^6*, Laimonas Griskevicius, MD^7*, Sandra Lejniece, MD^8*, Stefan Goranov, MD⁹, Liana Gercheva, MD^10*, Aleksandar Stojanovic, MD^11*, Dontcho Peytchev, MD^12*, Nikolay Tzvetkov, MD^13*, Rasa Griniute, MD^14*, Radka Oucheva, MD^15*, Hanno Ulmer, PhD^2*, Marthin Kwakkelstein, MD^16*, Gianluca Fincato, MD^17* and Guenther Gastl, MD^2*

¹Central European Leukemia Study Group (CELSG), Innsbruck, Krankenhaus Barmherzige Schwestern Linz, Linz, Austria
²Central European Leukemia Study Group (CELSG), Innsbruck, Austria
³CCRI Children Cancer Research Institute, Vienna, Austria
⁴Department of Hematology, RC Radiation Medicine, Kiev, Ukraine
⁵Institute of Blood Pathology and Transfusion Medicine, Lviv, Ukraine
⁶Clinical Center of Serbia, Institut za Hematologiju, Belgrad, Serbia and Montenegro
⁷Vilnius University Hospital Santariskiu Clinic, Vilnius, Lithuania
⁸National Center of Haematology, Riga, Latvia
⁹University Hospital for Active Treatment "St. George", Plovdiv, Bulgaria
¹⁰University Hospital for Active Treatment "St. Marina", Varna, Bulgaria
¹¹Clinic for Hematology, National Clinical Center Skopje, Skopje, Macedonia
¹²National Center of Hematology and Transfusiology, Sofia, Bulgaria
¹³University Hospital for Active Treatment, Pleven, Bulgaria
¹⁴Kaunas University Hospital, Kauna, Lithuania
¹⁵Alexandrovska University Hospital, Sofia, Bulgaria
¹⁶Novartis, Basel, Switzerland
¹⁷Novartis, Origgio VA, Italy

Huiren Chen^*, Yingjian Si^*, Xuepeng He^*, Kai Yang^*, Bo Hu^*, Zhenlan Du^*, Xiaomei Zhang^* and Chuancang Zhang^*

General Hospital of Beijing Millitary Region, Beijing, China

John J. Powers, B.S.^1*, Jeffrey S. Painter, B.S.^1*, Jason A Dubovsky, B.S.^1*, P.K. Epling-Burnette, PharmD, PhD² and Javier Pinilla, MD, PhD³

¹Immunology, H. Lee Moffitt Cancer Ctr. & Rsch. Inst., Tampa, FL
²James A Haley VA Hospital, H. Lee Moffitt Cancer Center, Tampa, FL
³H. Lee Moffitt Cancer Ctr., Tampa, FL