Gianantonio Rosti^1*, Fausto Castagnetti^1*, Angela Poerio^1*, Massimo Breccia^2*, Luciano Levato^3*, Adele Capucci^4*, Mario Tiribelli^5*, Fabio Stagno^6*, Alfonso Zaccaria^7*, Tamara Intermesoli^8*, Bruno Martino^9*, Monica Bocchia^10*, Michele Cedrone^11*, Francesco Bartucci^12*, Francesca Palandri^1*, Gabriele Gugliotta^1*, Nicoletta Testoni^1*, Giuliana Alimena¹³, Giovanni Martinelli^1*, Fabrizio Pane, MD¹⁴, Giuseppe Saglio^15* and Michele Baccarani^1*

¹Institute of Hematology Seragnoli, Bologna, Bologna, Italy
²University of Rome – La Sapienza, Italy
³Hematology Unit, Catanzaro, Italy
⁴Hematology Unit, Brescia, Italy
⁵Chair of Hematology, Udine, Italy
⁶Chair of Hematology, Catania, Italy
⁷Ematologia-Ravenna, Italy
⁸Chair of Hematology, Bergamo, Italy
⁹Reggio Calabria Hospital
¹⁰Chair of Hematology, University of Siena, Italy
¹¹Hematology Unit, "San Giovanni-Addolorata" Hospital, Roma, Italy
¹²Novartis Pharma, Origgio (VA), Italy
¹³Division of Hematology-Dept. of Cellular Biotechnologies and Hematology, University La Sapienza of Rome, Rome, Italy
¹⁴A.F. di Oncologia Ematologica Diagnostica, Azienda Ospedaliera, Napoli, Italy
¹⁵Internal Medicine and Hematology, Università di Torino - Ospedale San Luigi, Orbassano, Italy

Jorge Cortes, Susan O'Brien^*, Gautam Borthakur^*, Dan Jones^*, Farhad Ravandi^*, Charles Koller^*, Ofelia Mesina^*, Alessandra Ferrajoli^*, Jianqin Shan^* and Hagop Kantarjian^*

M.D. Anderson Cancer Center, Houston, TX

Francois Guilhot, MD¹, François-Xavier Mahon, MD, PhD^2*, Joelle Guilhot, MSci^1*, Francoise Rigual-Huguet, MD^3*, Frederic Maloisel, MD^4*, Philippe Rousselot, MD, PhD^5*, Martine Gardembas, MD^6*, Selim Corm, MD^7*, Agnes Guerci, MD, PhD^8*, Anne Vekhoff, MD^9*, Gabriel Etienne, MD^10*, Laurence Legros, MD^11*, Jean-Jacques Kiladjian, MD, PhD^12*, Eric Jourdan^13*, Michele Schoenwald, MD^14*, Marc Berger, MD^15*, Virginie Eclache, MD^16*, Catherine Roche-Lestienne, PhD^17*, Franck E Nicolini, MD, PhD¹⁸ and Claude Preudhomme, MD, PhD¹⁹

¹Cic 802 Inserm, CHU de Poitiers, Poitiers, France
²Université Victor Ségalen Bordeaux - Institut Bergonié, Bordeaux, France
³Hopital Purpan, Toulouse, France
⁴Centre de Strasbourg, France
⁵Hôpital Mignot and CIC9504, Versaille, France
⁶Haematology, CHU Angers, Angers, France
⁷Hematology department, Hôpital Huriez, Lille, France
⁸CHU Brabois, Nancy, France
⁹Hotel Dieu, Paris, France
¹⁰Hematopiese leucemique, Universite Victor Segalen INSERM U876, Bordeaux, France
¹¹Hematology department, Hôpital de l'Archet, Nice, France
¹²Hématologie Clinique, Assistance Publique - Hôpitaux de Paris, Hôpital Avicenne; Paris 13 University, Bobigny, France
¹³CHU de Nimes, Nimes, France
¹⁴Hopital La Source, Orleans, France
¹⁵CHU Hotel Dieu, Clermont Ferrant, France
¹⁶Hopital Avicenne
¹⁷Inserm U524, Lille, France
¹⁸Hematology Department, Hospital E. Herriot, Lyon, France
¹⁹Hopital Calmette, Lille, France

Ruediger Hehlmann, MD¹, Susanne Saussele, MD^1*, Michael Lauseker^2*, Ulrike Proetel, MD^1*, Elena Kovalevskaya, MD^1*, Armin Leitner, MD^1*, Claudia Haferlach, MD^3*, Brigitte Schlegelberger, MD⁴, Martin C Müller, MD^1*, Benjamin Hanfstein, MD^1*, Markus Pfirrmann, PhD^2*, Gerhard Ehninger⁵, Thomas Fischer, MD^6*, Joerg Hasford, MD^2*, Andreas Hochhaus, MD^1*, Dieter K. Hossfeld, MD, PhD^7*, Hans- Jochem Kolb, MD^8*, Stefan W Krause, MD^9*, Christoph Nerl, MD^10*, Hans Pralle, MD^11*, Alois Gratwohl¹², Andreas Tobler, MD¹³, Hermann Heimpel, MD^14* and The German CML Study Group^15*

¹Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany
²IBE University, München, Germany
³MLL, München, Germany
⁴Inst. of Cell & Molecular Pathology, MHH, Hannover, Germany
⁵Medical Clinic I, University Hospital, Dresden, Germany
⁶3. Medizinische Klinik, University, Mainz, Germany
⁷Onkologische Schwerpunktpraxis Lerchenfeld, Hamburg, Germany
⁸Transplantationseinheit, University, München, Germany
⁹Medizinische Klinik 5, Universitätsklinikum, Erlangen, Germany
¹⁰Krankenhaus Schwabing, München, Germany
¹¹Medizinische Klinik IV, Giessen, Germany
¹²University Hospital Basel, Basel, Switzerland
¹³Department of Hematology, Inselspital, Bern, Switzerland
¹⁴Medizinische Universitätsklinik und Poliklinik, University, Ulm, Germany
¹⁵Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Germany

Michele Baccarani¹, Fausto Castagnetti^2*, Bengt Simonsson^3*, Kimmo Porkka^4*, Ibrahim C. Haznedaroglu^5*, Arnon Nagler⁶, Francesca Palandri^2*, Giovanna Rege Cambrin^7*, Luciano Levato^8*, Fausto Palmieri^9*, Elisabetta Abruzzese¹⁰, Ugur Özbek^11*, Veli Kairisto^12*, Hans Bostrom^3*, Johann Lanng Nielsen^13*, Henrik Hjorth-Hansen^14*, Ole Weis-Bjerrum^15*, Nicoletta Testoni^2*, Giovanni Martinelli^16*, Fabrizio Pane, MD¹⁷, Giuseppe Saglio^7* and Gianantonio Rosti^2*

¹Department of Hematology and Oncological Sciences, University of Bologna, Bologna, Italy
²Dept. Hematology and Medical Oncology, University of Bologna, Bologna, Italy
³Hematology Unit, Uppsala University, Uppsala, Sweden
⁴Helsinki University Central Hospital, Helsinki, Hematology Research Unit, Finland
⁵Hematology, Hacettepe University, Ankara, Turkey
⁶Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Tel Hashomer, Israel
⁷Internal Medicine and Hematology, Università di Torino - Ospedale San Luigi, Orbassano, Italy
⁸Hematology Unit, Catanzaro, Italy
⁹Hematology Unit, Avellino, Italy
¹⁰S. Eugenio Hospital, Rome, Italy
¹¹Instanbul University, Instanbul, Turkey
¹²Turku University Central Hospital, Department of Medicine, Turku, Finland
¹³Aarhus University Hospital, Aarhus, Denmark
¹⁴St Olavs University Hospital, Trondheim, Norway
¹⁵Hematology Unit, Rigshospitalet, Copenhagen, Denmark
¹⁶Department of Hematology and Oncological Sciences, Seragnoli Institute, University of Bologna, Bologna, Italy
¹⁷A.F. di Oncologia Ematologica Diagnostica, Azienda Ospedaliera, Napoli, Italy

Stephen G O'Brien, MD, PhD^1*, François Guilhot, MD², John M Goldman, DM, FRCP^3*, Andreas Hochhaus, MD⁴, Timothy P Hughes, MD^5*, Jerald P. Radich, MD^6*, Marc Rudoltz, MD⁷, Jeiry Filian^7*, Insa Gathmann, M.Sc.^8*, Brian J. Druker, MD⁹ and Richard A. Larson, MD¹⁰

¹Department of Haematology, University of Newcastle, Newcastle, United Kingdom
²Clinical Investigational Centre INSERM 802, CHU Poitiers, Poitiers, France
³Department of Hematology, Imperial College London, Hammersmith Hospital, London, United Kingdom
⁴Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Germany
⁵Haematology, Institute of Medical and Veterinary Science, Adelaide, Australia
⁶Fred Hutchinson Cancer Research Ctr., Seattle, WA
⁷Oncology, Novartis Pharmaceutical, Inc., Florham Park, NJ
⁸Novartis Pharma AG, Basel, Switzerland
⁹Oregon Health & Science University Cancer Institute, Portland, OR
¹⁰University of Chicago, Chicago, IL

Francois-Xavier Mahon^1*, Francoise Huguet, MD^2*, Francois Guilhot, MD³, Laurence Legros, MD, PhD^4*, Franck E Nicolini, MD, PhD⁵, Aude Charbonnier^6*, Agnes Guerci, MD^7*, Delphine Rea, MD, PhD^8*, Bruno R. Varet, MD⁹, Martine Gardembas, MD^10*, Joelle Guilhot^3*, Gabriel Etienne^11*, Noel-Jean Milpied, MD, PhD¹², Emilie Aton^13*, Josy Reiffers^11* and Philippe Rousselot^14*

¹Hématopoïèse leucémique, Université Victor Segalen CHU de Bordeaux, Bordeaux, France
²Service d'Hématologie, Hôpital Purpan, Toulouse, France
³Cic-P 802 Inserm, CHU de Poitiers, Poitiers, France
⁴Service d'Hématologie, Hôpital de l'Archet, Nice, France
⁵Hematology Department, Hospital E. Herriot, Lyon, France
⁶Institut Paoli Calmette, Marseille, France
⁷Service d'Hématologie, CHU Brabois, Nancy, France
⁸Service Des Maladies Du Sang, Hôpital Saint Louis, Paris, France
⁹Hematology Dept., Paris Descartes Univ. Necker Hospital, Paris, France
¹⁰Haematology, CHU Angers, Angers, France
¹¹Institut Bergonié, Bordeaux, France
¹²Service des maladies du sang, Hopital Haut Leveque, Pessac, France
¹³Hopital Haut Leveque - Pessac, Bordeaux, France
¹⁴Centre André Mignot, Versaille, France

Franck E Nicolini, MD, PhD¹, Giovanni Martinelli^2*, Dong-Wook Kim, MD, PhD³, Andreas Hochhaus, MD⁴, Michael J. Mauro, MD⁵, Jorge Cortes, MD⁶, Charles Chuah, MBChB, MRCP, MD^7*, Inge Dufva, MD^8*, Jane F. Apperley, MBChB, FRCP, FRCPath⁹, Fumiharu Yagasaki, MD^10*, Jay Pearson, PhD^11*, Senaka Peter, MBA^11*, Cesar Sanz Rodriguez, MD^11*, Frank Giles, MD^12*, John M Goldman, DM, FCRP, FRCPath^13* and Wei Zhou, PhD^11*

¹Hematology Department, Hospital E. Herriot, Lyon, France
²Department of Hematology/Oncology “L. and A. Seràgnoli”, University of Bologna, Italy
³Hematology, St. Mary's Hospital, Seoul, South Korea
⁴Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim, Germany
⁵Oregon Health & Science University, Portland, OR
⁶M.D. Anderson Cancer Center, Houston, TX
⁷Hematology, Singapore General Hospital/Duke-NUS Graduate Medical School, Singapore, Singapore
⁸Department of Hematology, Herlev Hospital, University of Copenhagen, Herlev, Denmark
⁹Dept. of Haematology, Hammersmith Hospital, London, United Kingdom
¹⁰Japan Adult Leukemia Study Group, Japan
¹¹Merck Research Laboratories, White house station, NJ
¹²Institute for Drug Development, Cancer Therapy & Research Center, San Antonio, TX
¹³Dept of Haematology, Hammersmith hospital, London, United Kingdom