Susan O'Brien, M.D.¹, Gary Schiller², Robert Kenneth Stuart, MD³, Diana Hudak^4* and Francis Giles, MD⁵

¹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
²UCLA School of Medicine, Los Angeles, CA
³Medical Univ. of S. Caroline, Charleston, SC
⁴Vion Pharmaceuticals, Inc., New Haven, CT
⁵Inst. for Drug Development, Cancer Therapy, & Rsrch. Ctr., Univ. of Texas Health Sci. Ctr. at San Antonio, San Antonio, TX

Cristina Papayannidis^1*, Anna Candoni^2*, Stefania Paolini^1*, Emanuela Ottaviani^1*, Ilaria Iacobucci^1*, Michela Rondoni^3*, Michele Malagola^4*, Pier Paolo Piccaluga¹, Renato Fanin^2*, Giuseppe Visani^5*, Michele Baccarani¹, Domenico Russo⁴ and Giovanni Martinelli¹

¹Department of Hematology/Oncology L. and A. Seràgnoli, University of Bologna, Bologna, Italy
²Hematology, Udine University, Italy
³Haematology Department, University of Siena, Siena, Italy
⁴Hematology, University of Brescia, Brescia, Italy
⁵Department of Hematology, S. Salvatore Hospital, Pesaro, Italy

Lawrence Mayer, PhD^*, Wahseng Lim, PhD^*, Nancy Dos Santos, PhD^*, Sherwin Xie, PhD^*, Andrea Hopkins^*, Ruby Huang^*, Lindsey Wilkins^*, Sarah Kelly^*, David Bermudes, PhD^*, Troy Harasym, PhD^* and Paul Tardi, PhD^*

Celator Pharmaceuticals Corporation, Vancouver, BC, Canada

Jianxiang Wang, M.D.^*, Yingchang Mi, M.D., Ph.D., Jiazhuo Liu^*, Mingwei Fu^*, Ying Wang^*, Dong Lin^* and Shougeng Bian^*

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China

Yanina Eberhard^1*, Amudha Venugopal^1*, Marcela Gronda^1*, Rose Hurren^1*, Alessandro Datti^2*, Jeff Wrana^2*, William E Antholine^3* and Aaron D. Schimmer¹

¹Princess Margaret Hospital, Toronto, ON, Canada
²Mount Sinai Hospital, Toronto, ON, Canada
³National Biomedical EPR Center, Medical College of Wisconsin, Milwaukee, WI

Charles Craddock, BM, DPhil, FRCP, FRCPath^1*, Nicolas Goardon^2*, Mike Griffiths^1*, James D. Cavenagh, MD³, Shamyla Siddique^1* and Paresh Vyas, BM, DPhil, FRCP, FRCPath²

¹Haematology, University Hospital Birmingham, Birmingham, United Kingdom
²MRC Molecular Haematology Unit and Dept of Haematology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
³Dept. of Hematology, St. Bartholomew's Hospital, London, ARRAY(0xc16de94)

Jin Zhou, MD, and, PhD^1*, Ran Meng, MD, and, PhD^2*, Xinhua Sui, MD^3*, Guosheng Feng, MD, and, PhD^3* and Baoyu Li, PhD^4*

¹Hematology, the dean of the first hospital affiliated harbin medical university,China,150001, Harbin, China
²Neurology, Division of Neurology , Shijitan Hospital, The Ninth Clinical Medical College of Beijing University, Beijing, China 100038, Beijing, China
³Surgery, Shijitan Hospital, The Ninth Clinical Medical College of Beijing University, Beijing, China 100038, Beijing, China
⁴Hematology, Shijitan Hospital, The Ninth Clinical Medical College of Beijing University, Beijing, China 100038, Beijing, China

Allan D. Hess, PhD, Christian Meyer^*, Christopher Thoburn^*, Ferdynand Kos^*, Christopher Gocke^*, Hyam Levitsky^* and Judith Karp^*

Oncology, The Johns Hopkins University, Baltimore, MD

Hua Yan^1*, Zhi-Xiang Shen, MD^1* and Jianxiang Wang^2*

¹Rui Jin Hospital, Shanghai, China
²Chinese Academy of Medical Sciences, Institute of Hematology and Blood Diseases Hospital,, Tianjin, China

Susan O'Brien, M.D.¹, David A. Rizzieri, MD², Norbert Vey, MD³, Hagop M Kantarjian⁴, Tove Flem Jacobsen^5*, Bo I Nilsson, MD, PhD^5*, Karin Staudacher^5* and Francis Giles, MD⁶

¹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
²Cellular Therapy, Duke Univ. Med. Ctr., Durham, NC
³Dept. of Hematology, Institut Paoli Clamettes, Marseille, France
⁴The University of Texas M. D. Anderson Cancer Center, Houston, TX
⁵Clinical, Clavis Pharma ASA, Oslo, Norway
⁶Inst. for Drug Development, Cancer Therapy, & Rsrch. Ctr., Univ. of Texas Health Sci. Ctr. at San Antonio, San Antonio, TX

Andrew L Muranyi, BSc^1*, Shoukat Dedhar, PhD^2* and Donna E. Hogge, MD, PhD¹

¹Terry Fox Laboratory, B.C. Cancer Agency, Vancouver, BC, Canada
²Cancer Genetics, B.C. Cancer Agency, Vancouver, BC, Canada

Dushyant Verma, MD, FACP, Stefan Faderl, MD, Susan O'Brien, MD^*, Sherry Pierce^*, Jorge Cortes, MD^*, Khanh Vu, MD^*, Emil Freireich, MD^*, Michael J. Keating, MBBS^*, Hagop M. Kantarjian, MD^* and Farhad Ravandi, MBBS

M.D. Anderson Cancer Center, Houston, TX

Amer Zeidan^1*, Wei Tan^2*, Gregory Wilding^2*, LaurieAnn Ford^3*, Theresa Hahn, PhD², Shannon Smiley, MD², Minoo Battiwalla, MD², Philip L. McCarthy, MD², Eunice S. Wang, MD² and Meir Wetzler, MD⁴

¹Rochester General Hospital, Rochester, NY
²Roswell Park Cancer Institute, Buffalo, NY
³Medicine, Roswell Park Cancer Institute, Buffalo, NY
⁴Roswell Park Cancer Inst., Buffalo, NY

Linda Resar, M.D.¹, Joelle Hillion, Ph.D.^1*, Katrina Alino, R.N., B.S.N.^2*, Michelle Rudek, Pharm.D., Ph.D.^2* and Judith Karp, M.D.^2*

¹Medicine; Div. of Hematology, Johns Hopkins University SOM, Baltimore, MD
²Oncology, Johns Hopkins University SOM, Baltimore, MD

Bruno C. Medeiros, MD¹, Jason R. Gotlib^1*, Steven E. Coutre^1*, Angela Mignea, Clinical, Research, Coordinator^2* and James Zehnder^1*

¹Stanford Cancer Center, Stanford Univ., Stanford, CA
²Medicine, Stanford University, Stanford, CA

Anjali Advani, MD¹, Edward A. Copelan, MD¹, Ronald Sobecks, MD¹, Mikkael A Sekeres, MD, MS¹, Jennifer Bates^1*, Mary Lynn Rush^1*, Barbara Tripp^1*, Elysa Noon, PhD^2*, Matthew Howard, MD^3*, Tao Jin^4*, Eric Hsi, MD³ and Matt Kalaycio, MD¹

¹Hematologic Oncology and Blood Disorders, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH
²Novartis Pharmaceuticals, Florham Park, NJ
³Clinical Pathology, Cleveland Clinic, Cleveland, OH
⁴Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

Martin S Tallman¹, George B McDonald^2*, Laurie D DeLeve^3*, Eliot Obi-Tabot^4*, Carl Kollmer^4* and Jay M Feingold⁵

¹Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
²University of Washington, Seattle, WA
³University of Southern California, Los Angeles, CA
⁴Wyeth Pharmaceuticals, Collegeville, PA
⁵Wyeth Pharmaceuticals, Cambridge, MA

PierLuigi Tazzari, MD^1*, Veronica Papa, BS^2*, Francesca Ricci, BS^1*, Francesca Chiarini, BS^2*, Camilla Evangelisti, PhD^2*, Giovanni Martinelli, MD³, Andrea Bontadini, MD^1*, James McCubrey, PhD⁴ and Alberto M. Martelli, MD²

¹Transfusion Center, Policlinico S.Orsola-Malpighi, Bologna, Italy
²Dept. of Human Anatomical Sci., Univ. of Bologna, Bologna, Italy
³Hematology and Oncology, University of Bologna
⁴School of Medicine, East Carolina University, Greenville, NC

Oliver G. Ottmann, MD^1*, Andrew Spencer², H. Miles Prince³, Kapil N. Bhalla^4*, Thomas Fischer^5*, Angela Liu^6*, Kathryn Parker^6*, Muhammad Jalaluddin^7*, Glen Laird^6*, Margaret Woo^6*, Jeffrey W. Scott^6* and Daniel J. DeAngelo^8*

¹Medizinische Klinik II, University of Frankfurt, Frankfurt, Germany
²Clinical Haematology & BMT, Alfred Hospital, Melbourne, Australia
³Department of Haematology, Peter MacCallum Cancer Center, Melbourne, Australia
⁴Medical College of Georgia Cancer Center, Augusta, GA
⁵Department of Hematology/Oncology, University of Magdeburg, Magdeburg, Germany
⁶Novartis Oncology, Florham Park, NJ
⁷Novartis Pharmaceuticals Corporation, Florham Park, NJ
⁸Adult Oncology, Dana-Farber Cancer Institute, Boston, MA

Beverly Lange, MD¹, Richard K Yang^2*, Jacek Gan, PhD^2*, Jaqueline A Hank, PhD^3*, Eric Sievers, MD⁴, Robert Gerbing^5*, Todd Alonzo, PhD⁶ and Paul M Sondel, MD, PhD^2*

¹Oncology, Children's Hosp. of Philadelphia, Philadelphia, PA
²Pediatrics, University of Wisconsin School of Medicine, Madison
³Humonc, University of Wisconsin School of Medicine, Madison
⁴Seattle Genetics, Inc., Bothell, WA
⁵Children's Oncology Group, Arcadia, CA
⁶Keck School of Med., Univ. of Southern California, Arcadia, CA

Hervé Dombret¹, Claude Gardin^2*, Sylvie Chevret^3*, Cecile Pautas^4*, Pascal Turlure^5*, Xavier Thomas⁶, Bruno Quesnel^7*, Thierry de Revel^8*, Christine Terré^9*, Pierre Fenaux², Dominique Bordessoule^5* and Sylvie Castaigne⁹

¹Acute Leukemia French Association (ALFA), Hôpital Saint-Louis, Paris, France
²Hôpital Avicenne, Bobigny, France
³Department of Biostatistics (DBIM), Hôpital Saint-Louis, Paris, France
⁴Hôpital Henri Mondor, Créteil, France
⁵CHU, Limoges, France
⁶Hôpital Edouard Herriot, Lyon, France
⁷CHU, Lille, France
⁸Hôpital Percy, Clamart, France
⁹Hôpital Mignot, Versailles, France

B. Lowenberg, MD¹, F. Davies, MD², C. Müller-Tidow, MD^3*, Ulrich Dührsen^4*, A. Burnett, MD, FRCP⁵, P. Zachée, MD, PhD⁶, D. Dierickx, MD^7*, C. Jenkins, MD^5*, P. Sonneveld, MD^1*, M. Jongen-Lavrencic, MD^1*, S. Zweegman, MD^8*, G. Morgan, MD^2*, U. Krug, MD^3*, A. Richardson, PhD^9*, L. Hooftman, MD^9* and G. Ossenkoppele, MD, PhD⁸

¹Erasmus University Medical Center, Rotterdam, Netherlands
²Institute of Cancer Research, Sutton, United Kingdom
³University Hospital, Münster, Germany
⁴University Hospital, Essen, Germany
⁵University Hospital, Cardiff, United Kingdom
⁶ZNA, Antwerp, Belgium
⁷University Hospital, Leuven, Belgium
⁸VU University Medical Center, Amsterdam, Netherlands
⁹Chroma Therapeutics Ltd, Abingdon, United Kingdom

Rose Ann Padua, PhD¹, Kouichi Furugaki, MD, PhD^2*, Helene Moins-Teisserenc, MD, PhD^2*, Katerina Pokorna^1*, Carole Le Pogam^1*, Murielle Reboul^1*, Masayuki Aoki, PhD^1*, Veronique Bajzik^2*, Patricia Krief, PhD^1*, Anne Janin, MD, PhD^3*, Maria-Elena Noguera, MD^4*, Robert West, PhD^5*, Marie-Helene Schlageter, PhD^1*, Dominique Charron, MD, PhD^2*, Marika Pla, PhD^1* and Christine Chomienne, MD, PhD¹

¹Inserm U718, Institut Universitaire d'Hematologie, Paris, France
²Inserm U662, Institut Universitaire d'Hematologie, Paris, France
³Inserm U728, Institut Universitaire d'Hematologie, Paris, France
⁴Departement d'Hematologie, AP-HP, Hopital Saint Louis, Paris, France
⁵Wales Heart Institute, University of Cardiff, United Kingdom

Annette Sander, MD^1*, Martin Zimmermann, PhD^2*, Dirk Reinhardt, MD, PhD³, Michael Dworzak, MD, PhD^4*, Gertjan Kaspers, MD, PhD^5* and Ursula Creutzig, MD, PhD⁶

¹Pediatric Hematology Oncology, Hannover Medical School, Hannover, Germany
²Pediatric Hematology/Oncology, Medical School Hannover, Hannover, Germany
³Pediatric Hematology and Oncology, Medical School Hannover, Hannover, Germany
⁴St. Anna Children's Hospital
⁵Pediatric Hematology/Oncology, VU University Medical Center, Amsterdam, Netherlands
⁶Pediatric Hematology/Oncology, Universitats-Kinderklinik Munster, Munster, Germany

Stefan Faderl, Gautam Borthakur^*, Farhad Ravandi^*, Xuelin Huang^*, Miloslav Beran^*, Alessandra Ferrajoli^*, Charles A. Koller^*, Deborah A. Thomas^*, Srdan Verstovsek^*, Monica Kwari^* and Hagop M. Kantarjian^*

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX