50th ASH Annual Meeting and Exposition (December 6 - 9, 2008): The Hemopoietic Microenvironment and the Clinic

Monday, December 8, 2008: 1:30 PM-3:00 PM

Gateway Ballroom 103 - South (Moscone Center)

Moderators:

Louise Purton and Russell Taichman, MD

1:30 PM

547

Osteoclast Function Is Essential in the Hematopoietic Stem Cell Niche

Stefania Lymperi^*, Nikki Horwood^* and Francesco Dazzi^*

Stem Cell Biology Section, Imperial College, London, United Kingdom

1:45 PM

548

Circadian Expression of Endothelial Selectins, Regulated by the Sympathetic Nervous System, Controls Peripheral Leukocyte Homeostasis

Yuya Kunisaki, M.D, Ph.D¹^*, Daniel Lucas, PhD²^* and Paul S. Frenette, M.D.³

¹Department of Medicine, Mount Sinai School of Medicine, New York, NY
²Mount Sinai School of Medicine, New York, NY
³Department of Medicine and Immunology Institute, Mount Sinai School of Medicine, New York, NY

2:00 PM

549

Mesenchymal Stem Cells (MSC) Are Not Intrinsically Immune Privileged: Direct Demonstration in TCR Transgenic Mice and by Imaging of Allogeneic Luciferase+ MSC in Immune Competent Vs Immune Deficient Mice

Lior Zangi¹^*, Andreas Beilhack²^*, Robert Negrin, MD³, Raanan Margalit¹^* and Yair Reisner¹^*

¹Immunology, Weizmann Institute of Science, Rehovot, Israel
²Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA
³Stanford University, Stanford, CA

2:15 PM

550

Detection of Functional Hematopoietic Stem Cell Niche Using Real-Time Imaging

Tong Yin¹^*, Yucai Xie¹^*, Winfried Wiegraebe²^*, Xi He¹ and Linheng Li¹^*

¹Stowers Institute for Medical Research, Kansas City, MO
²Advanced Instrumentation and Physics, Stowers Institute for Medical Research, Kansas city, MO

2:30 PM

551

Bone Marrow Adipocytes Prevent Hematopoietic Expansion in Homeostasis and in Bone Marrow Transplantation

Olaia Naveiras, M.D.¹^*, Valentina Nardi, MD²^* and George Q. Daley, MD, PhD³

¹Hematology/Oncology, Children's Hospital Boston, Boston, MA
²Children's Hospital, Boston, MA
³Children's Hospital Boston, Boston, MA

2:45 PM

552

Solid Tumors Target the HSC Niche to Establish Metastatic Footholds in the Marrow

Yusuke Shiozawa¹^*, Elisabeth A. Pedersen¹^*, Aaron M. Havens¹^*, Younghun Jung¹^*, Anne M. Ziegler¹^*, Michael J. Pienta¹^*, Junhui Song¹^*, Jingcheng Wang¹^*, Robert D. Loberg²^*, Paul H. Krebsbach¹^*, Kenneth J. Pienta²^* and Russell S Taichman¹

¹University of Michigan Dental School, Ann Arbor, MI
²University of Michigan Medical School, Ann Arbor, MI

See more of: Oral and Poster Abstracts

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^*signifies non-member of ASH

506.O2.6 The Hemopoietic Microenvironment and the Clinic