50th ASH Annual Meeting and Exposition (December 6 - 9, 2008): Cellular Interactions in HSC Niche Biology.

Monday, December 8, 2008: 11:00 AM-12:30 PM

Gateway Ballroom 103 - South (Moscone Center)

Moderators:

Amy Wagers and Arun Balakumaran, MD, PhD

11:00 AM

Functional SDF-1 Secretion from BM Stromal Cells Is a Cell Contact-Dependent Event Mediated by Cx43 and Cx45 Gap-Junctions

Amir Schajnovitz, MSc¹^*, Tomer Itkin, MSc¹^*, Aya Ludin, DMD, MSc¹^*, Alexander Kalinkovich, MD, PhD¹^*, Kfir Lapid, MSc¹^*, Rony Seger, PhD²^* and Tsvee Lapidot, PhD¹

¹Department of Immunology, Weizmann Institute of Science, Rehovot, Israel
²Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel

11:15 AM

320

Endosteal Niches and Lymphopoiesis Are Inhibited during G-CSF-Induced Hematopoietic Stem Cell Mobilization

Jean-Pierre Levesque, PhD¹, Natalie A Sims, PhD²^*, Linda J Bendall, PhD³^*, Yi Shen¹^* and Ingrid G Winkler, PhD¹^*

¹Mater Medical Research Institute, South Brisbane, Australia
²St Vincent's Institute, Fitzroy, Australia
³Westmead Insitute for Cancer Research, Westmead, Australia

11:30 AM

321

Erythropoietin Stimulates Bone Formation In Vivo By Targeting Both HSCs and MSCs

Younghun Jung^*, Anne Ziegler^*, Yusuke Shiozawa^*, Zhuo Wang^*, Junhui Song^*, Jianhua Wang^*, Jincheng Wang^*, Michael J. Pienta^*, Clara H. Lee^*, Aaron M. Havens^*, Elisabeth A. Pedersen^*, Paul H. Krebsbach^* and Russell S. Taichman

University of Michigan Dental School, Ann Arbor, MI

11:45 AM

322

Reciprocal Synergistic Interactions of Leukemic Cells with Osteoclast Progenitors in the Bone Microenvironment

Benjamin Frisch¹^*, John M Ashton²^*, Adam Olm-shipman³^*, Lianping Xing¹^*, Craig T. Jordan, PhD⁴ and Laura Calvi, MD⁵

¹Department of Pathology, University of Rochester School of Medicine and Dentistry, Rochester, NY
²Department of Genetics, University of Rochester School of Medicine and Dentistry, Rochester, NY
³Department of Medicine, University of Rochester, Rochester, NY
⁴Univ. of Rochester Medical Ctr., Rochester, NY
⁵Univ. of Rochester, Sch. of Med., Rochester, NY

12:00 PM

323

Bone Marrow Monocyte/Macrophages Provide Signals Necessary for Osteoblast Maintenance: Potential Role for Insulin-Like Growth Factor Signaling

Matthew Christopher, PhD^* and Daniel C. Link, MD

Washington University School of Medicine, Saint Louis, MO

12:15 PM

324

Role of the Urokinase Receptor (uPAR) in the Cross-Talk of Hematopoietic Stem Cells with the Bone Marrow Microenvironment

Nunzia Montuori, PhD¹^*, Patrizia Ricci²^*, Bianca Serio²^*, Valeria Visconte, PhD³^*, Claudio La Penna¹^*, Ada Pesapane¹^*, Antonio M. Risitano, MD, PhD², Bruno Rotoli⁴^*, Guido Rossi¹^*, Pia Ragno, PhD¹^* and Carmine Selleri²^*

¹Molecular and Cellular Biology and Pathology, Federico II University, Naples, Italy
²Hematology, Federico II, Naples, Italy
³NHLBI, NIH, Bethesda, MD
⁴Hematology, Federico II, Napoli, Italy

See more of: Oral and Poster Abstracts

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^*signifies non-member of ASH

506.O1.6 Cellular Interactions in HSC Niche Biology.