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502.O1.6 Nonhematopoietic Stem and Progenitor Cells

Monday, December 8, 2008: 11:00 AM-12:30 PM
Gateway Ballroom 104 - South (Moscone Center)
Moderators:
Graca Almeida-Porada, MD, PhD and Massimo Dominici
11:00 AM
The Unique Pattern of Somatic Imprint in Oct-4+ Very Small Embryonic Like (VSEL) Stem Cells Isolated from Adult Tissues Further Supports Both Their Epiblast/Germ Line Origin and Explains Quiescent Status: Potential Modification of Somatic Imprint as a Key to Longevity?

Dong-Myung Shin, Ph.D.*, Ewa K Zuba-Surma, Ph.D.*, Mariusz Z Ratajczak, M.D., Ph.D. and Magdalena Kucia

James Graham Brown Cancer Center, Stem Cell Institute University of Louisville, Louisville, KY

11:15 AM
Patient-Specific Induced Pluripotent Stem Cells in Hurler Syndrome

Jakub Tolar, MD, PhD1, In-Hyun Park, M.D.2*, Lily Xia, B.S.1*, Mark Osborn, B.S.1*, Ron T. McElmurry, B.S.1*, Paul J. Orchard, M.D.1*, George Q. Daley, MD, PhD3 and Bruce R Blazar, M.D.1

1Univ. of Minnesota, Minneapolis, MN
2Division of Hematology, Harvard Medical School, Boston, MA
3Children's Hospital Boston, Boston, MA

11:30 AM
Epithelial Cells of Donor Origin after Allogeneic HCT: Result of Cell Fusion, Transdifferentiation (plasticity) or Transfer of Epithelial Cell Precursors with the Graft?

Faisal Khan, PhD1*, Sarah Sy1*, Polly Louie1*, Megan Smith1*, Judy Chernos1*, Robyn Lee1*, Noureddine Berka1*, Gary D. Sinclair1*, Richard Leigh1*, David Proud1*, James A. Russell2 and Jan Storek, MD, PhD1

1University of Calgary, Calgary, AB, Canada
2Tom Baker Cancer Centre, Calgary, AB, Canada

11:45 AM
Tissue-Specific Gene Expression of Marrow Cells Co-Cultured with Various Murine Organs

Jason M. Aliotta, MD*, Mandy Pereira* and Peter J. Quesenberry, MD

Hematology/Oncology, Rhode Island Hospital, Center for Stem Cell Biology Research, Providence, RI

12:00 PM
Reprogrammed Murine Fibroblasts Differentiated into Hematopoietic Progenitors Are Able to Successfully Engraft and Repopulate the Bone Marrow

Zaida Alipio*, Dan Xu*, Jianchang Yang*, Louis M. Fink, Wilson Xu*, David C Ward* and Yupo Ma

Nevada Cancer Institute, Las Vegas, NV

12:15 PM
Tales from the Crypt: Mesenchymal Stem Cells for Replenishing the Intestinal Stem Cell Pool

Evan Colletti, PhD1*, Deena ElShabrawy, M.D., Doc.2*, Esmail D. Zanjani, PhD1*, Christopher D Porada, PhD1* and Graca Almeida-Porada, MD, PhD1

1Animal Biotechnology, University of Nevada, Reno, Reno, NV
2Clinical Pathology Department, Zagazig University, Cairo, Egypt

*signifies non-member of ASH