Willem M Lijfering, MD^*, René Mulder^*, Min Ki ten Kate^*, Andre Mulder^* and Jan van der Meer^*

University Medical Center Groningen, Groningen, Netherlands

Cihan Ay^1*, Alexandra Kaider^2*, Silvia Koder^3*, Peter Husslein, MD^4* and Ingrid Pabinger⁵

¹Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
²Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Vienna, Austria
³Division of Haematology and Haemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria
⁴Department of Obstetrics and Gynecolocy, Medical University of Vienna, Vienna, Austria
⁵Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria

Hadia Shbaklo, PhD^1*, Christina A Holcroft, ScD^1* and Susan R Kahn, MD, MSc²

¹Centre for Clinical Epidemiology and Community Studies, Jewish General Hospital, Montreal, QC, Canada
²Division of Internal Medicine, Department of Epidemiology and Biostatistics, McGill University, Montreal, QC, Canada

Marc Carrier, MD¹, Marc Righini, MD^2*, Reza Karami Djurabi^3*, Menno Huisman^3*, Arnaud Perrier, MD^4*, Philip Wells, MD, FRCPC, MSc⁵, Walter Wuillemin^6* and Gregoire Le Gal, MD, PhD^7*

¹University of Ottawa, Ottawa, ON, Canada
²Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland
³Leiden University, Leiden, Netherlands
⁴Geneva University Hospital, Geneva, Switzerland
⁵Ottawa Hospital Civic Site, Ottawa, ON, Canada
⁶Haematology and Central Haematology Laboratory Kantonsspital, Lucerne, Switzerland
⁷Medicine, Ottawa Health Research Institute, Ottawa, ON, Canada

Frank Leebeek, MD, PhD¹, Yuana Yuana^2*, Suzanne Osanto^2*, Moniek de Maat^1*, Hajo Auwerda^1*, Rogier Bertina^3* and Pieter Sonneveld, MD, PhD¹

¹Hematology, Erasmus Medical Center, Rotterdam, Netherlands
²Oncology, LUMC, Leiden, Netherlands
³Hematology, LUMC, Leiden, Netherlands

Bas De Laat, PhD¹, Philip G. de Groot, PhD^2*, Ronald H.W.M. Derksen, MD., PhD^3*, Rolf T. Urbanus^4*, Koen Mertens, PhD¹, Frits Rosendaal, MD, PhD⁵ and Carine J.M. Doggen, PhD^5*

¹Department of Plasma Proteins, Sanquin Blood Supply Foundation, Amsterdam, Netherlands
²Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, Netherlands
³Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
⁴Department of Clinical Chemistry and Haematology, University Medical Center, Utrecht, Utrecht, Netherlands
⁵Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

Shoshana Revel-Vilk, MD¹, Joanne Yacobovich, MD^2*, Hannah Tamary, MD², Gal Goldstein, MD^3*, Isaac Yaniv, MD², Amos Toren, MD, PhD³, Polina Stephanski, MD^1*, Michael Weintraub, MD^1* and Gili Kenet, MD⁴

¹Pediatric Hematology/Oncology Department, Hadassah Hebrew-University Hospital, Jerusalem, Israel
²Pediatric Hematology/Oncology Department, Schneider Children's Medical Center, Petah Tikva, Israel
³Pediatric Hematology/Oncology Department, The Chaim Sheba Medical Center, Tel Hashomer, Israel
⁴Thrombosis Unit, The Chaim Sheba Medical Centre, Tel Hashomer, Israel

Hendrika M Knol^1*, Nic J.G.M. Veeger^1*, Saskia Middeldorp^2*, Karly Hamulyàk^3*, Martin H Prins^4*, Harry R Büller^2* and Jan van der Meer^1*

¹Division of Haemostasis, Thrombosis and Rheology, University Medical Center Groningen, Groningen, Netherlands
²Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands
³Hematology, University Hospital Maastricht, Maastricht, Netherlands
⁴Clinical epidemiology and medical technology assessment, University Hospital Maastricht, Maastricht, Netherlands

Christopher Hueser, DO, MS^1*, Anjali J Patel, DO^2* and John N Allan, BS^3*

¹Hematology and Oncology, St. Louis University, Saint Louis, MO
²Anesthesiology and Critical Care, St. Louis University, St. Louis, MO
³St. Louis University Medical School, St. Louis, MO

Flora Peyvandi^1*, Marta Spreafico^1*, Luisa Foco^2*, Luisa Bernardinelli^3*, Stefano Duga^4*, Rosanna Asselta^4*, Diego Ardissino^5*, Sekar Kathiresan^6*, Pierangelica Merlini^7* and Pier M. Mannucci, MD⁸

¹Department of Medicine and Medical Specialties, University of Milan, IRCCS Maggiore Hospital, Milan, Milan, Italy
²Dipartimento di Scienze Sanitarie Applicate e Psicocomportamentali, Università di Pavia, Pavia, Italy
³MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, United Kingdom
⁴Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
⁵Division of Cardiology, Maggiore Hospital, University of Parma, Parma, Italy
⁶Cardiology Division, Massachusetts General Hospital, Boston, MA
⁷Division of Cardiology, Azienda Ospedaliera Niguarda Ca' Granda, Milan, Italy
⁸Department of Medicine and Medical Specialties, University of Milan , IRCCS Maggiore Hospital, Milano, Italy

Stephen J. Everse, Ph.D.^1*, Thomas Orfeo, Ph.D.^2*, Kathleen E. Brummel-Ziedins, Ph.D.^2*, Matthew F. Hockin, Ph.D.^3* and Kenneth G. Mann, Ph.D.²

¹Biochemistry, University of Vermont, Burlington, VT
²Biochemistry, University of Vermont, Colchester, VT
³Human Genetics Operations, University of Utah, Salt Lake City, UT

Karim Abou-Nassar, MD^1*, Marc Carrier, MD² and Marc Rodger, MD, FRCPC³

¹Hematology, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada
²University of Ottawa, Ottawa, ON, Canada
³General Campus, Ottawa Hospital, Ottawa, ON, Canada

Vladimir Bogdanov, PhD¹, Giovanni Cimmino, MD^2*, Jonathan G Tardos, MD^1*, Brian G Choi, MD^2*, Annapoorna Kini, MD^2*, Samin K Sharma, MD^2*, Sharad Kothari, MBBS^2*, James R Tunstead, PhD^2*, Sajiv Chandradas, BS^1*, Bjarne Østerud, PhD^3* and Juan J Badimon, PhD^2*

¹Mount Sinai School of Medicine, New York, NY
²The Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY
³Biochemistry, Institute of Medical Biology, University of Tromsø, Tromsø, Norway

Jennifer Latella, MD^1*, Sylvie Desmarais, MD^2*, Susan Kahn, MD³ and Veto Investigators^4*

¹Medicine, McGill University, Montreal, QC, Canada
²Medicine, Hopital Pierre Boucher, Montreal, QC, Canada
³Center for Clinical Epidemiology and Community Studies, Montreal, QC, Canada
⁴Quebec and Ontario

Jennifer Eglinton^1*, Paul Harrison^2*, Helen Segal^3*, Louise Silver^3*, Ziyah Mehta^3* and Peter Rothwell^3*

¹Department of Haematology, Oxford Radcliffe NHS Trust, Oxford, United Kingdom
²Oxford Haemophilia & Thrombosis Centre, Churchill Hospital, Oxford, United Kingdom
³Stroke Prevention Research Unit, Department of Clinical Neurology, University of Oxford, Oxford, United Kingdom

Veysel sabri Hancer^1*, Reyhan Diz-Kucukkaya^2* and Aysegul topal-Sarikaya^3*

¹Hematology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
²Hematology, Istanbul Faculty of Medicine, Istanbul University, Gokturk, Istanbul, Turkey
³Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul, Turkey

Uma Athale, MD¹, Albert Moghrabi, MD², Trishna Nayiager, BScH^3*, Delva Yves-Line^4*, Lehana Thabane, Ph.D.^5* and Anthony Chan, MBBS⁶

¹Div. of Pediatric Hematology/Oncology, McMaster University, Hamilton, ON, Canada
²Room A-490, St. Justine Hospital, Montreal, QC, Canada
³Pediatrics, McMaster Children's Hospital, Hamilton, Canada
⁴Clinical Research Hematology/Oncology, Hospital Ste. Justine, Montreal, Canada
⁵Ce & B, McMaster University, Hamilton, Canada
⁶McMaster University, Hamilton, ON, Canada

Jacqueline Kuziej^1*, Evangelos Litinas^2*, Debra Hoppensteadt^2*, Dahui Liu, Ph.D.^3*, Jeanine M. Walenga, PhD⁴, Jawed Fareed, PhD⁵ and Walter Jeske^6*

¹Loyola University Medical Center, Maywood, IL
²Pathology, Loyola University Medical Center, Maywood, IL
³PolyMedix, Inc., Radnor, PA
⁴Cardiovascular Institute, Loyola Univ. Medical Center, Maywood, IL
⁵Loyola Univ. Medical Ctr., Maywood, IL
⁶Cardiovascular Institute, Loyola University Medical Center, Maywood, IL

Alexander Gatt, MD, MRCP, FRCPath^1*, Anne Riddell^1*, Vincenza Calvaruso^2*, Michael Makris, MD³, Edward Tuddenham^4* and Andrew Burroughs^2*

¹Hemophilia Ctr. & Thrombosis Unit, The Royalfree Hospital, London, United Kingdom
²Royal Free Hospital, London,UK, Hepatology and Liver Transplantation Unit, London, United Kingdom
³Dept. of Haematology, Sheffield Teaching Hospitals Trust, Sheffield, ARRAY(0xc0e07c8)
⁴Hemophilia Ctr. & Thrombosus Unit, The Royalfree Hospital, London, ARRAY(0xc7e9c90)

Ilka Warshawsky, MD, PhD^1*, Vinit Makkar, MD^2* and Kandice Kottke-Marchant, MD, PhD³

¹Clinical Pathology, Cleveland Clinic Foundation, Cleveland, OH
²Hematology and Medical Oncology, Cleveland Clinic Beachwood, Beachwood, OH
³Clinical Pathology, Cleveland Clinic, Cleveland, OH

Michael B. Streiff, MD¹, Xiaobu Ye, MD^2*, Serena Desideri, MD^2*, Thomas Kickler, MD^3*, Jayesh Jani^3* and Stuart Grossman, MD^2*

¹Johns Hopkins Medical Institutions, Baltimore, MD
²Oncology, Johns Hopkins Medical Institutions, Baltimore, MD
³Pathology, Johns Hopkins Medical Institutions, Baltimore, MD