50th ASH Annual Meeting and Exposition (December 6 - 9, 2008): Vascular Wall Biology and Endothelial Progenitor Cells

Monday, December 8, 2008: 3:30 PM-5:30 PM

2002-2004 - West (Moscone Center)

Moderators:

Elaine Majerus, MD, PhD and Robert Handin

3:30 PM

689

Platelets Regulate Tumor-Induced Angiogenesis

Yali Chang^*, Jing Zhang, Huifeng Lin^*, Joseph Italiano^* and Robert I. Handin^*

Department of Medicine, Brigham and Women's Hospital, Boston, MA

3:45 PM

690

In Vivo Imaging of Large-Vessel Thrombosis

Brian C. Cooley, Ph.D.

Medical College of Wisconsin, Milwaukee, WI

4:00 PM

691

Endothelium but Not Platelet-Derived Protein Disulfide Isomerase Is Required for Fibrin Generation during Thrombus Formation in Vivo.

Reema Jasuja, PhD¹^*, Jaehyung Cho, PhD², Bruce Furie, MD² and Barbara Furie²^*

¹Beth Israel Deaconess Med Ctr, Boston, MA
²Beth Israel Deaconess Med. Ctr., Boston, MA

4:15 PM

692

Protein Phosphatase 2B Inhibition Promotes the Secretion of Von Willebrand Factor from Endothelial Cells

Leticia Nolasco¹^*, Francisca C. Gushiken, MD², Vimal Patel, BS³^*, Nancy Turner¹^*, Subhashree Pradhan, Ph.D.²^*, Jing-fei Dong, MD, PhD², Joel L. Moake, MD⁴ and K. Vinod Vijayan, PhD⁵

¹Rice University, Houston, TX
²Baylor College of Medicine, Houston, TX
³Medicine, Baylor College of Medicine, Houston, TX
⁴Rice Univ., Baylor College of Medicine, Bellaire, TX
⁵Thrombosis Research Center, Baylor College of Medicine, Houston, TX

4:30 PM

693

In Vitro and in Vivo Characterization of Human Embryonic Stem Cell- Derived CD34⁺ Cells That Function as Pericytes with Endothelial Cell and Smooth Muscle Cell Potential

Katherine L. Hill¹^*, Petra Obrtlikova, MD¹^*, Diego F Alvarez, MD, PhD²^*, Judy A King, MD²^*, Qinglu Li, DVM¹^*, Jianyi Zhang, MD, PhD¹^* and Dan S. Kaufman, MD, PhD¹

¹Medicine, University of Minnesota, Minneapolis, MN
²Internal Medicine, University of South Alabama, Mobile, AL

4:45 PM

694

Depletion of Vascular Endothelial Progenitor Cells Inhibits Inflammation

Olaf Penack¹^*, Erik Henke¹^*, David Suh¹^*, Christopher King¹^*, Marsinay O Smith¹^*, Il-Kang Na, MD¹^*, Amanda Holland¹^*, Arnab Ghosh¹^*, Sydney X Lu¹^*, Robert Jenq²^*, Chen Liu³^*, George F Murphy⁴^*, Theresa Lu⁵^*, Chad May⁶^*, David A. Scheinberg, MD, PhD¹^*, Ding Cheng Gao⁵^*, Vivek Mittal⁵^*, Robert Benezra¹^* and Marcel Van Den Brink, MD, PhD¹

¹Memorial-Sloan-Kettering Cancer Center, New York City, NY
²Memorial-Sloan-Kettering Cancer Center, New York, NY
³Department of Pathology, University of Florida School of Medicine, Gainesville, FL
⁴Harvard Medical School
⁵Weill Cornell Medical College
⁶ImClone Systems Incorporated

5:00 PM

695

Activation of the PI3K-Akt Pathway by Activated Protein C Occurs Via a Novel Receptor, Apolipoprotein E Receptor 2 (ApoER2)

Xia V. Yang, PhD¹^*, Yajnavalka Banerjee, PhD¹^*, Jose A. Fernandez, MD, PhD¹, Hiroshi Deguchi, MD, PhD¹^*, Xiao Xu¹^*, Laurent O. Mosnier, PhD¹, Rolf T Urbanus, MD²^*, Phillip G deGroot, PhD²^*, Tara C White³^*, Owen J.T. McCarty, PhD³^* and John H. Griffin, PhD¹

¹Molecular & Experimental Medicine, The Scripps Research Institute, La Jolla, CA
²Laboratory of Clinical Chemistry and Haematology, University Medical Centre Utrecht, Utrecht, Netherlands
³Division of Biomedical Engineering, Oregon Health and Science University School of Medicine, Portland, OR

5:15 PM

696

TRAF-1 Deficient Mice Show Impaired Monocyte Recruitment and Decreased Atherogenesis

Anna Missiou, MD¹^*, Natascha Köstlin, MS¹^*, Christian Münkel, MA¹^*, Dietmar Pfeifer, PhD²^*, Katja Zirlik, MD², Christoph Bode, MD¹^*, Peter Libby, MD³^* and Andreas Zirlik, MD¹^*

¹Cardiology, University of Freiburg, Freiburg, Germany
²Hematology and Oncology, University of Freiburg, Freiburg, Germany
³Brigham and Women's Hospital, Boston, MA

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^*signifies non-member of ASH

302.O2.8 Vascular Wall Biology and Endothelial Progenitor Cells