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201.O2.6 Contribution of Myeloid and Progenitor Cells to Tissue Regeneration and Inflammation

Monday, December 8, 2008: 1:30 PM-3:00 PM
Yerba Buena Ballroom Salon 7 (San Francisco Marriott)
Moderators:
Marie-Dominique Filippi, PhD and Mary C. Dinauer, MD, PhD
1:30 PM
469
The Zinc Finger Protein Gfi1 Controls TLR4-Mediated Inflammatory Response by Directly Antagonizing NF-κB Transcription Factor

Ehssan Sharif-Askari, PhD1*, Hui Zeng, MD, PhD2*, Lothar Vassen, PhD1*, Christian Kosan, PhD1*, Cyrus Khandanpour, MD1, Florian Heyd, PhD1* and Tarik Moroy, PhD1

1Institut de recherches cliniques de Montreal - IRCM, Montreal, QC, Canada
2Insitute of Infectious disease, Beijing Ditan Hospital, Beijing, China
1:45 PM
470
Stem Cell Factor Signaling Collaborates in the Development of FIP1L1/PDGFRα Induced Chronic Eosinophilic Leukemia in a Murine Model

Yoshiyuki Yamada, MD, PhD1, Marc E Rothenberg, MD, PhD2*, Melissa McBride2*, Abel Sanchez-Aguilera, PhD3* and Jose Cancelas, MD, PhD4

1Allergy/Immunology, Gunma Children's Medical Ctr., Shibukawa, Gunma, Japan
2Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
3Hematology/Oncology, Boston Children's Hospital, Boston, MA
4Hoxworth Blood Center, Univ. of Cincinnati, Cincinnati, OH
2:00 PM
471
Conditioning of Monocytes in the Bone Marrow by Inflammatory Cytokines Inhibits Their Angiogenic Potential at Peripheral Sites of Ischemia

Alyssa D. Gregory*, Benjamin J. Capoccia, PhD* and Daniel C. Link, MD

Internal Medicine, Washington University School of Medicine, Saint Louis, MO
2:15 PM
472
CCR2 Mediates Hematopoietic Stem/Progenitor Cell Trafficking to Peripheral Tissues after Inflammation

Yue Si, PhD*, Chia-Lin Tsou, MS* and Israel Charo, MD, PhD*

Gladstone Institute of Cardiovascular Disease and Department of Medicine, University of California, San Francisco, San Francisco, CA
2:30 PM
473
Transcription Factors PU.1 and EGR2 Inhibits the Oncogenic Microrna Cluster Mir-17-92 during Macrophage Differentiation

Vit Pospisil1*, Karin Vargova1*, Pavel Burda1*, Juraj Kokavec1*, Emanuel Necas1*, Jiri Zavadil2* and Tomas Stopka, MD, PhD1

1Pathological Physiology and Center of Experimental Hematology, First Faculty of Medicine, Charles University, Prague, Czech Republic
2Langone Medical Center, New York University, New York, NY
2:45 PM
474
Mobilization of Hematopoietic Progenitors Following Myocardial Ischemic Injury Underpins the Physiological and Therapeutic Benefits of G-CSF on Myocardial Repair

David J. Curtis, MD, PhD1, Peter Kanellakis2* and Alex Bobik, PhD2*

1Rotary Bone Marrow Rsch. Lab., RMH Research Foundation, Parkville, VIC, Australia
2Cell Biology, Baker Medical Research Institute, Melbourne, Australia
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