Norman N. Iscove, MD, PhD
Dr. Norman Iscove has made significant and pioneering contributions to hemopoietic stem cell research that advanced the field in both methodology and concept. In recent years, his laboratory has concentrated on identifying genes that specify the sustained capacity for self-renewal that uniquely characterizes the long-term reconstituting stem cells. Dr. Iscove is currently Senior Scientist at the Ontario Cancer Institute in Toronto.
Donald Metcalf, MD
Dr. Donald Metcalf is well known for his pioneering work on the regulation of blood cell formation. Beginning in 1965, he worked to co-develop specialized culture techniques for growing blood cells, which led to the discovery of colony-stimulating factors (CSFs), hormones that regulate white blood cell formation. Dr. Metcalf’s work led to the successful cloning and mass production of CSFs, which can speed recovery in cancer patients following chemotherapy or radiation therapy. Dr. Metcalf has received many prestigious honors during his career, including the Lasker Award for Clinical Medicine, the Louisa Gross Horwitz Prize of Columbia University, and the Jessie Stevenson Kovalenko Medal of the U.S. National Academy of Sciences. He is currently Professor Emeritus at the University of Melbourne in Australia.
Stuart H. Orkin, MD
Dr. Stuart Orkin is a renowned stem cell biologist, and, over the past decade, his research has focused on identifying critical nuclear regulators of hematopoiesis. Dr. Orkin’s work on the molecular pathology of inherited blood disorders also greatly improved the ability to diagnose and treat these conditions. Among numerous other accolades, he received one of ASH’s highest honors, the William Dameshek Prize, in 1986. Currently, Dr. Orkin is the David G. Nathan Professor of Pediatrics at Harvard Medical School and a Howard Hughes Medical Institute investigator.
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