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Pioneers in Hemostasis

Sunday, December 7, 2008: 11:00 AM-12:30 PM
301 - South (Moscone Center)
Moderator:
Menaka Pai, MD
Co-chairs:
Earl W. Davie, PhD , Kenneth G. Mann, PhD and Pier M. Mannucci, MD

Earl W. Davie, PhD
Dr. Earl Davie’s research, spanning more than four decades, has elucidated many areas of the coagulation cascade and led to effective treatments for patients with hemophilia. With colleagues, he devised the revolutionary theory that proteins in the blood plasma are activated by minor proteolysis in order for blood to clot and then proceeded to identify and characterize these proteins in detail throughout the 1960s and 70s. Later, with new DNA technologies, he also isolated, sequenced, and expressed the genes for these clotting factors. For these critical achievements, Dr. Davie received the Society’s most prestigious award, the Stratton Medal, in 1993. He is currently a biochemistry professor at the University of Washington in Seattle.

Kenneth G. Mann, PhD
Dr. Kenneth Mann, an internationally known researcher, has made key discoveries regarding coagulation, including the isolation and characterization of blood-clotting factor V and the prothrombinase complex, and the description of the mechanisms of action of pro- and anticoagulants. He has more than four decades of experience in the field of hemostasis, holds several patents relating to his research, and has published more than 450 original papers, reviews, and chapters. For his work, Dr. Mann has received numerous national and international awards, including the Stratton Medal and E. Donnall Thomas Award from ASH. Dr. Mann is currently Professor of Biochemistry and Medicine at the University of Vermont College of Medicine in Colchester.

Pier Mannucci, MD
Dr. Pier Mannucci has been a respected authority on hemostasis and thrombosis for more than 30 years. Particularly well known for his work on hemophilia and von Willebrand disease, Dr. Mannucci developed new drugs to treat patients with these disorders. He has received numerous awards for his work, including the Robert Grant Medal and the International Prize on Hemophilia, and has served as president of the International Society of Thrombosis and Haemostasis. He delivered the Ham-Wasserman lecture in 2002 and is listed as one of the most highly cited scientists in clinical medicine by the Institute for Scientific Information. Currently, Dr. Mannucci serves as Chairman of the Department of Internal Medicine and Medical Specialties at the University of Milan.

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